No association of germline alteration of MSR1 with prostate cancer risk

Liang Wang, Shannon K. McDonnell, Julie M Cunningham, Scott Hebbring, Steven J. Jacobsen, James R Cerhan, Susan L Slager, Michael L. Blute, Daniel J Schaid, Stephen N Thibodeau

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

The macrophage scavenger receptor 1 gene (MSR1) was recently identified as a candidate susceptibility gene for hereditary prostate cancer and as a risk factor for sporadic prostate cancer. To confirm these findings, we screened MSR1 for germline mutations among individuals with familial prostate cancer and tested gene variants for associations in both sporadic and familial prostate cancer. Our results do not support MSR1 as a risk factor for prostate cancer.

Original languageEnglish (US)
Pages (from-to)128-129
Number of pages2
JournalNature Genetics
Volume35
Issue number2
DOIs
StatePublished - Oct 1 2003

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Scavenger Receptors
Prostatic Neoplasms
Genes
Germ-Line Mutation
Neoplasm Genes
Familial Prostate cancer

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

Cite this

No association of germline alteration of MSR1 with prostate cancer risk. / Wang, Liang; McDonnell, Shannon K.; Cunningham, Julie M; Hebbring, Scott; Jacobsen, Steven J.; Cerhan, James R; Slager, Susan L; Blute, Michael L.; Schaid, Daniel J; Thibodeau, Stephen N.

In: Nature Genetics, Vol. 35, No. 2, 01.10.2003, p. 128-129.

Research output: Contribution to journalArticle

Wang, Liang ; McDonnell, Shannon K. ; Cunningham, Julie M ; Hebbring, Scott ; Jacobsen, Steven J. ; Cerhan, James R ; Slager, Susan L ; Blute, Michael L. ; Schaid, Daniel J ; Thibodeau, Stephen N. / No association of germline alteration of MSR1 with prostate cancer risk. In: Nature Genetics. 2003 ; Vol. 35, No. 2. pp. 128-129.
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