TY - JOUR
T1 - Nitrosyl haemoglobin
T2 - The no-spin as a relaxation probe in the solvent-proton magnetic resonance experiment demonstrating the phosphate-induced widening of the haem-pocket
AU - Benko, B.
AU - Vuk-Pavlović, S.
PY - 1976/8/23
Y1 - 1976/8/23
N2 - This communication presents evidence that nitric oxide bound to ferrous haem-iron of haemoglobin is a powerful relaxation probe in the solvent-proton magnetic resonance experiments. When such an experiment is applied to the interaction of human haemoglobin with inositol hexaphosphate, it shows that phosphate increases the solvent-dynamics in the haem-pockets, consistent with their widening. Some implications of these findings are discussed here.
AB - This communication presents evidence that nitric oxide bound to ferrous haem-iron of haemoglobin is a powerful relaxation probe in the solvent-proton magnetic resonance experiments. When such an experiment is applied to the interaction of human haemoglobin with inositol hexaphosphate, it shows that phosphate increases the solvent-dynamics in the haem-pockets, consistent with their widening. Some implications of these findings are discussed here.
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U2 - 10.1016/0006-291X(76)90796-8
DO - 10.1016/0006-291X(76)90796-8
M3 - Article
C2 - 184787
AN - SCOPUS:0017128639
SN - 0006-291X
VL - 71
SP - 1303
EP - 1307
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 4
ER -