Nitric oxide and physiologic vasodilation in human limbs: Where do we go from here?

Michael J. Joyner, Michael E. Tschakovsky

Research output: Contribution to journalReview articlepeer-review

30 Scopus citations

Abstract

This brief review highlights human studies on the role of nitric oxide (NO) and limb vasodilation conducted at the Mayo Clinic over the last 10 years. These studies have attempted to determine whether NO is responsible for the "unexplained" limb vasodilation seen with body heating, limb ischemia, exercise, and mental stress. Our findings are placed in context with data from others, and possible future areas of study are identified.

Original languageEnglish (US)
Pages (from-to)475-490
Number of pages16
JournalCanadian Journal of Applied Physiology
Volume28
Issue number3
DOIs
StatePublished - Jun 2003

Keywords

  • Exercise hyperemia
  • Mental stress
  • Reactive hyperemia
  • Skin blood flow

ASJC Scopus subject areas

  • Physiology
  • Orthopedics and Sports Medicine

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