NIMH collaborative multisite multimodal treatment study of children with ADHD: I. Background and rationale

J. E. Richters, L. E. Arnold, P. S. Jensen, H. Abikoff, C. K. Conners, L. L. Greenhill, L. Hechtman, S. P. Hinshaw, W. E. Pelham, J. M. Swanson

Research output: Contribution to journalArticle

225 Citations (Scopus)

Abstract

Objective: The National Institute of Mental Health's recently initiated 5- year, multisite, multimodal treatment study of children with attention- deficit hyperactivity disorder (MTA) is the first major clinical trial in its history focused on a childhood mental disorder. This article reviews the major scientific and clinical bases for initiating the MTA. Method: A selective review of the literature is presented in the service of describing the estimated prevalence of ADHD among children and adolescents, its core clinical features, evidence concerning psychopharmacological and psychosocial treatment effects, and related research issues and trends leading to the development of the MTA. Results: Despite decades of treatment research and clinical practice, there is an insufficient basis for answering the following manifold question: under what circumstances and with what child characteristics (comorbid conditions, gender, family history, home environment, age, nutritional/metabolic status, etc.) do which treatments or combinations of treatment (stimulants, behavior therapy, parent training, school-based intervention) have what impacts (improvement, stasis, deterioration) on what domains of child functioning (cognitive, academic, behavioral, neurophysiological, neuropsychological, peer relations, family relations), for how long (short versus long term), to what extent (effect sizes, normal versus pathological range), and why (processes underlying change)? Conclusions: The important scientific, clinical, and public health issues nested within this manifold question provide both the impetus and scaffolding for the MTA.

Original languageEnglish (US)
Pages (from-to)987-1000
Number of pages14
JournalJournal of the American Academy of Child and Adolescent Psychiatry
Volume34
Issue number8
StatePublished - 1995
Externally publishedYes

Fingerprint

Pemetrexed
National Institute of Mental Health (U.S.)
Combined Modality Therapy
Family Relations
Behavior Therapy
Pathologic Processes
Therapeutics
Attention Deficit Disorder with Hyperactivity
Nutritional Status
Research
Mental Disorders
Public Health
History
Clinical Trials

Keywords

  • attention-deficit hyperactivity disorder
  • childhood disorders
  • multimodal treatment
  • psychopharmacological treatment
  • psychosocial treatment

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Developmental and Educational Psychology

Cite this

Richters, J. E., Arnold, L. E., Jensen, P. S., Abikoff, H., Conners, C. K., Greenhill, L. L., ... Swanson, J. M. (1995). NIMH collaborative multisite multimodal treatment study of children with ADHD: I. Background and rationale. Journal of the American Academy of Child and Adolescent Psychiatry, 34(8), 987-1000.

NIMH collaborative multisite multimodal treatment study of children with ADHD : I. Background and rationale. / Richters, J. E.; Arnold, L. E.; Jensen, P. S.; Abikoff, H.; Conners, C. K.; Greenhill, L. L.; Hechtman, L.; Hinshaw, S. P.; Pelham, W. E.; Swanson, J. M.

In: Journal of the American Academy of Child and Adolescent Psychiatry, Vol. 34, No. 8, 1995, p. 987-1000.

Research output: Contribution to journalArticle

Richters, JE, Arnold, LE, Jensen, PS, Abikoff, H, Conners, CK, Greenhill, LL, Hechtman, L, Hinshaw, SP, Pelham, WE & Swanson, JM 1995, 'NIMH collaborative multisite multimodal treatment study of children with ADHD: I. Background and rationale', Journal of the American Academy of Child and Adolescent Psychiatry, vol. 34, no. 8, pp. 987-1000.
Richters, J. E. ; Arnold, L. E. ; Jensen, P. S. ; Abikoff, H. ; Conners, C. K. ; Greenhill, L. L. ; Hechtman, L. ; Hinshaw, S. P. ; Pelham, W. E. ; Swanson, J. M. / NIMH collaborative multisite multimodal treatment study of children with ADHD : I. Background and rationale. In: Journal of the American Academy of Child and Adolescent Psychiatry. 1995 ; Vol. 34, No. 8. pp. 987-1000.
@article{e2295d3ea1bd42e08b925d446d937bb2,
title = "NIMH collaborative multisite multimodal treatment study of children with ADHD: I. Background and rationale",
abstract = "Objective: The National Institute of Mental Health's recently initiated 5- year, multisite, multimodal treatment study of children with attention- deficit hyperactivity disorder (MTA) is the first major clinical trial in its history focused on a childhood mental disorder. This article reviews the major scientific and clinical bases for initiating the MTA. Method: A selective review of the literature is presented in the service of describing the estimated prevalence of ADHD among children and adolescents, its core clinical features, evidence concerning psychopharmacological and psychosocial treatment effects, and related research issues and trends leading to the development of the MTA. Results: Despite decades of treatment research and clinical practice, there is an insufficient basis for answering the following manifold question: under what circumstances and with what child characteristics (comorbid conditions, gender, family history, home environment, age, nutritional/metabolic status, etc.) do which treatments or combinations of treatment (stimulants, behavior therapy, parent training, school-based intervention) have what impacts (improvement, stasis, deterioration) on what domains of child functioning (cognitive, academic, behavioral, neurophysiological, neuropsychological, peer relations, family relations), for how long (short versus long term), to what extent (effect sizes, normal versus pathological range), and why (processes underlying change)? Conclusions: The important scientific, clinical, and public health issues nested within this manifold question provide both the impetus and scaffolding for the MTA.",
keywords = "attention-deficit hyperactivity disorder, childhood disorders, multimodal treatment, psychopharmacological treatment, psychosocial treatment",
author = "Richters, {J. E.} and Arnold, {L. E.} and Jensen, {P. S.} and H. Abikoff and Conners, {C. K.} and Greenhill, {L. L.} and L. Hechtman and Hinshaw, {S. P.} and Pelham, {W. E.} and Swanson, {J. M.}",
year = "1995",
language = "English (US)",
volume = "34",
pages = "987--1000",
journal = "Journal of the American Academy of Child and Adolescent Psychiatry",
issn = "0890-8567",
publisher = "Elsevier Limited",
number = "8",

}

TY - JOUR

T1 - NIMH collaborative multisite multimodal treatment study of children with ADHD

T2 - I. Background and rationale

AU - Richters, J. E.

AU - Arnold, L. E.

AU - Jensen, P. S.

AU - Abikoff, H.

AU - Conners, C. K.

AU - Greenhill, L. L.

AU - Hechtman, L.

AU - Hinshaw, S. P.

AU - Pelham, W. E.

AU - Swanson, J. M.

PY - 1995

Y1 - 1995

N2 - Objective: The National Institute of Mental Health's recently initiated 5- year, multisite, multimodal treatment study of children with attention- deficit hyperactivity disorder (MTA) is the first major clinical trial in its history focused on a childhood mental disorder. This article reviews the major scientific and clinical bases for initiating the MTA. Method: A selective review of the literature is presented in the service of describing the estimated prevalence of ADHD among children and adolescents, its core clinical features, evidence concerning psychopharmacological and psychosocial treatment effects, and related research issues and trends leading to the development of the MTA. Results: Despite decades of treatment research and clinical practice, there is an insufficient basis for answering the following manifold question: under what circumstances and with what child characteristics (comorbid conditions, gender, family history, home environment, age, nutritional/metabolic status, etc.) do which treatments or combinations of treatment (stimulants, behavior therapy, parent training, school-based intervention) have what impacts (improvement, stasis, deterioration) on what domains of child functioning (cognitive, academic, behavioral, neurophysiological, neuropsychological, peer relations, family relations), for how long (short versus long term), to what extent (effect sizes, normal versus pathological range), and why (processes underlying change)? Conclusions: The important scientific, clinical, and public health issues nested within this manifold question provide both the impetus and scaffolding for the MTA.

AB - Objective: The National Institute of Mental Health's recently initiated 5- year, multisite, multimodal treatment study of children with attention- deficit hyperactivity disorder (MTA) is the first major clinical trial in its history focused on a childhood mental disorder. This article reviews the major scientific and clinical bases for initiating the MTA. Method: A selective review of the literature is presented in the service of describing the estimated prevalence of ADHD among children and adolescents, its core clinical features, evidence concerning psychopharmacological and psychosocial treatment effects, and related research issues and trends leading to the development of the MTA. Results: Despite decades of treatment research and clinical practice, there is an insufficient basis for answering the following manifold question: under what circumstances and with what child characteristics (comorbid conditions, gender, family history, home environment, age, nutritional/metabolic status, etc.) do which treatments or combinations of treatment (stimulants, behavior therapy, parent training, school-based intervention) have what impacts (improvement, stasis, deterioration) on what domains of child functioning (cognitive, academic, behavioral, neurophysiological, neuropsychological, peer relations, family relations), for how long (short versus long term), to what extent (effect sizes, normal versus pathological range), and why (processes underlying change)? Conclusions: The important scientific, clinical, and public health issues nested within this manifold question provide both the impetus and scaffolding for the MTA.

KW - attention-deficit hyperactivity disorder

KW - childhood disorders

KW - multimodal treatment

KW - psychopharmacological treatment

KW - psychosocial treatment

UR - http://www.scopus.com/inward/record.url?scp=0029023201&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029023201&partnerID=8YFLogxK

M3 - Article

C2 - 7665456

AN - SCOPUS:0029023201

VL - 34

SP - 987

EP - 1000

JO - Journal of the American Academy of Child and Adolescent Psychiatry

JF - Journal of the American Academy of Child and Adolescent Psychiatry

SN - 0890-8567

IS - 8

ER -