NIH initiative to balance sex of animals in preclinical studies: Generative questions to guide policy, implementation, and metrics

Louise D. McCullough, Geert J. De Vries, Virginia M. Miller, Jill B. Becker, Kathryn Sandberg, Margaret M. McCarthy

Research output: Contribution to journalReview article

70 Scopus citations

Abstract

In May of 2014, the NIH Director together with the Director of the Office of Research on Women's Health announced plans to take a multi-dimensional approach to address the over reliance on male cells and animals in preclinical research. The NIH is engaging the scientific community in the development of policies to improve the sex balance in research. The present, past, and future presidents of the Organization for the Study of Sex Differences, in order to encourage thoughtful discussion among scientists, pose a series of questions to generate ideas in three areas: 1. research strategies, 2. educational strategies, and 3. strategies to monitor effectiveness of policies to improve the sex balance in research. By promoting discussion within the scientific community, a consensus will evolve that will move science forward in a productive and effective manner. Keywords: Gender, Sexual dimorphism, Sex differences

Original languageEnglish (US)
Article number15
JournalBiology of Sex Differences
Volume5
Issue number1
DOIs
StatePublished - Oct 1 2014

ASJC Scopus subject areas

  • Gender Studies
  • Endocrinology

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