Nicotine blood levels and short-term smoking reduction with an electronic nicotine delivery system

Mitchell A. Nides; Scott J. Leischow; Meghna Bhatter; Michael Simmons

doi:10.5993/AJHB.38.2.12

Nicotine blood levels and short-term smoking reduction with an electronic nicotine delivery system

Mitchell A. Nides, Scott J. Leischow, Meghna Bhatter, Michael Simmons

Quantitative Health Sciences

Research output: Contribution to journal › Article › peer-review

75 Scopus citations

Abstract

Objectives: To evaluate nicotine delivery from the NJOY® King Bold Electronic Nicotine Delivery System (ENDS) and its short-term potential for smoking reduction or cessation. Methods: One week of ad libitum use was followed by measurements of plasma nicotine, heart rate, and craving and withdrawal after 12 hours of nicotine abstinence in 25 adult smokers not interested in quitting. Results: After 5 minutes of use, blood nicotine levels increased by a mean of 3.5 ng/mL (p < .001), heart rate increased, and craving was reduced by 55%. Cigarettes per day were reduced by 39% during the test week, and perceptions of use for reduction or cessation were positive. Conclusions: The NJOY® King Bold ENDS delivers nicotine and led to short-term smoking reduction. Copyright (c) PNG Publications. All rights reserved.

Original language	English (US)
Pages (from-to)	265-274
Number of pages	10
Journal	American Journal of Health Behavior
Volume	38
Issue number	2
DOIs	https://doi.org/10.5993/AJHB.38.2.12
State	Published - Mar 2014

Keywords

Electronic cigarette
Nicotine delivery
Smoking cessation

ASJC Scopus subject areas

Health(social science)
Social Psychology
Public Health, Environmental and Occupational Health

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10.5993/AJHB.38.2.12

Cite this

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abstract = "Objectives: To evaluate nicotine delivery from the NJOY{\textregistered} King Bold Electronic Nicotine Delivery System (ENDS) and its short-term potential for smoking reduction or cessation. Methods: One week of ad libitum use was followed by measurements of plasma nicotine, heart rate, and craving and withdrawal after 12 hours of nicotine abstinence in 25 adult smokers not interested in quitting. Results: After 5 minutes of use, blood nicotine levels increased by a mean of 3.5 ng/mL (p < .001), heart rate increased, and craving was reduced by 55%. Cigarettes per day were reduced by 39% during the test week, and perceptions of use for reduction or cessation were positive. Conclusions: The NJOY{\textregistered} King Bold ENDS delivers nicotine and led to short-term smoking reduction. Copyright (c) PNG Publications. All rights reserved.",

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AU - Nides, Mitchell A.

AU - Leischow, Scott J.

AU - Bhatter, Meghna

AU - Simmons, Michael

PY - 2014/3

Y1 - 2014/3

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AB - Objectives: To evaluate nicotine delivery from the NJOY® King Bold Electronic Nicotine Delivery System (ENDS) and its short-term potential for smoking reduction or cessation. Methods: One week of ad libitum use was followed by measurements of plasma nicotine, heart rate, and craving and withdrawal after 12 hours of nicotine abstinence in 25 adult smokers not interested in quitting. Results: After 5 minutes of use, blood nicotine levels increased by a mean of 3.5 ng/mL (p < .001), heart rate increased, and craving was reduced by 55%. Cigarettes per day were reduced by 39% during the test week, and perceptions of use for reduction or cessation were positive. Conclusions: The NJOY® King Bold ENDS delivers nicotine and led to short-term smoking reduction. Copyright (c) PNG Publications. All rights reserved.

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KW - Nicotine delivery

KW - Smoking cessation

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Nicotine blood levels and short-term smoking reduction with an electronic nicotine delivery system

Abstract

Keywords

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