NF-κB links oestrogen receptor signalling and EMT

Derek C. Radisky, Mina J. Bissell

Research output: Contribution to journalArticle

34 Scopus citations

Abstract

The detrimental effects of nuclear factor-kappa B (NF-κB) signalling in cancer cells lacking the oestrogen receptor have now become clear, with the demonstration that increased NF-κB levels induce expression of Bcl-2 to both suppress apoptosis and induce epithelial-mesenchymal transitions (EMTs).

Original languageEnglish (US)
Pages (from-to)361-363
Number of pages3
JournalNature Cell Biology
Volume9
Issue number4
DOIs
StatePublished - Apr 1 2007

ASJC Scopus subject areas

  • Cell Biology

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