NF-κB links oestrogen receptor signalling and EMT

Derek C. Radisky; Mina J. Bissell

doi:10.1038/ncb0407-361

NF-κB links oestrogen receptor signalling and EMT

Derek C. Radisky, Mina J. Bissell

Cancer Biology

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

The detrimental effects of nuclear factor-kappa B (NF-κB) signalling in cancer cells lacking the oestrogen receptor have now become clear, with the demonstration that increased NF-κB levels induce expression of Bcl-2 to both suppress apoptosis and induce epithelial-mesenchymal transitions (EMTs).

Original language	English (US)
Pages (from-to)	361-363
Number of pages	3
Journal	Nature Cell Biology
Volume	9
Issue number	4
DOIs	https://doi.org/10.1038/ncb0407-361
State	Published - Apr 1 2007

ASJC Scopus subject areas

Cell Biology

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title = "NF-κB links oestrogen receptor signalling and EMT",

abstract = "The detrimental effects of nuclear factor-kappa B (NF-κB) signalling in cancer cells lacking the oestrogen receptor have now become clear, with the demonstration that increased NF-κB levels induce expression of Bcl-2 to both suppress apoptosis and induce epithelial-mesenchymal transitions (EMTs).",

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AB - The detrimental effects of nuclear factor-kappa B (NF-κB) signalling in cancer cells lacking the oestrogen receptor have now become clear, with the demonstration that increased NF-κB levels induce expression of Bcl-2 to both suppress apoptosis and induce epithelial-mesenchymal transitions (EMTs).

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NF-κB links oestrogen receptor signalling and EMT

Abstract

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