New Information on the genetics of stroke

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

Ischemic stroke, white matter hyperintensities related to small vessel ischemia, and intracranial aneurysms all show heritability. This review focuses on recent progress in understanding the molecular genetics of these disorders. Also reviewed is recent progress in understanding single-gene disorders in which stroke is a major feature of the phenotype, including CADASIL, CARASIL, hereditary angiopathy with nephropathy, aneurysm and muscle cramps, and Fabry disease and progress in pharmacogenomics as it relates to response to antiplatelet therapy.

Original languageEnglish (US)
Pages (from-to)35-41
Number of pages7
JournalCurrent neurology and neuroscience reports
Volume11
Issue number1
DOIs
StatePublished - Feb 1 2011

Keywords

  • CADASIL
  • CARASIL
  • Cerebral aneurysm
  • Cost effectiveness
  • Fabry disease
  • Family history
  • Genetics genomics
  • Ischemic stroke
  • Leukoaraiosis
  • Pharmacogenomics
  • White matter hyperintensities

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

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