New hope for symptom management during natural and iatrogenic menopause transitions

Teresa K. Woodruff, Sundeep Khosla

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Bone loss is associated with aging and is exacerbated by female transition tomenopause. Estrogen has long been associated with bone loss, and replacement therapy is effective at restoring bone health. In the last 10 years, pituitary and gonadal peptide hormones have been implicated in bone biology, and here we update the story on FSH and its potential role as a direct regulator of bone and adipose. If translated to humans, new approaches to ameliorate age related bone demise could be developed. Moreover, young women with hormone responsive cancers who are unable to maintain bone may have new routes to avoid debilitating bone loss.

Original languageEnglish (US)
Pages (from-to)177-178
Number of pages2
JournalBiology of Reproduction
Volume97
Issue number2
DOIs
StatePublished - Aug 1 2017

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Keywords

  • Breast cancer
  • Estradiol
  • Fertility
  • FSH
  • Osteoporosis

ASJC Scopus subject areas

  • Cell Biology

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