New frontiers in therapeutic EUS

Dreams, style exercises or actual possibilities

A. M. Buchner, M. B. Wallace

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The term therapeutic endoscopic ultrasound (EUS) refers to direct ultrasound guided placement of pharmaceuticals, devices and biological agents for the purpose of treating a disease or symptoms. The vast majority of EUS procedures in the world are performed for diagnostic purposes, although these lead directly to therapeutic decisions such as whether to treat diseases by local (including endoscopic) resection, surgery or chemotherapy. EUS imaging is providing directions for therapies in different conditions, such as 1) gastrointestinal (GI) diseases including luminal GI malignancies, 2) management of pancreatic pain by performing the celiac plexus block, 3) drainage of obstructed biliary and pancreatic ducts when standard ERCP methods have failed, and 4) lesions surrounding the gut wall, including adjacent organs (pancreas liver, etc) and mediastinum (e.g. non-small cell lung cancer staging). Experimental promising EUS applications include delivery of cytotoxic agents such as chemotherapy, gene therapy, and radioactive seeds. This article will review the diagnostic and therapeutic role of EUS in gastrointestinal as well as extra-intestinal diseases.

Original languageEnglish (US)
Pages (from-to)287-298
Number of pages12
JournalMinerva Medica
Volume98
Issue number4
StatePublished - Aug 2007

Fingerprint

Celiac Plexus
Drug Therapy
Intestinal Diseases
Neoplasm Staging
Gastrointestinal Diseases
Endoscopic Retrograde Cholangiopancreatography
Pancreatic Ducts
Cytotoxins
Biological Factors
Mediastinum
Pain Management
Therapeutics
Non-Small Cell Lung Carcinoma
Genetic Therapy
Drainage
Pancreas
Ultrasonography
Seeds
Equipment and Supplies
Liver

Keywords

  • Endoscopy
  • Gastrointestinal diseases
  • Ultrasonography

ASJC Scopus subject areas

  • Medicine(all)

Cite this

New frontiers in therapeutic EUS : Dreams, style exercises or actual possibilities. / Buchner, A. M.; Wallace, M. B.

In: Minerva Medica, Vol. 98, No. 4, 08.2007, p. 287-298.

Research output: Contribution to journalArticle

Buchner, AM & Wallace, MB 2007, 'New frontiers in therapeutic EUS: Dreams, style exercises or actual possibilities', Minerva Medica, vol. 98, no. 4, pp. 287-298.
Buchner, A. M. ; Wallace, M. B. / New frontiers in therapeutic EUS : Dreams, style exercises or actual possibilities. In: Minerva Medica. 2007 ; Vol. 98, No. 4. pp. 287-298.
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