Abstract
In this article, we highlight recent Bipolar Collaborative Network data. We found that childhood-onset bipolar illness is common, often goes untreated for more than a decade, and carries a poor prognosis. During randomized studies of adjunctive medications in depression: 1) Venlafaxine showed higher switch rates than bupropion or sertraline; 2) Tranylcypromine was as well tolerated as lamotrigine; and 3) Modafinil was more effective than placebo. Finally, in treatment of overweight and obesity, topiramate and sibutramine showed equal efficacy but poor tolerability, and zonisamide data showed that it may be useful for mood and weight loss.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 489-497 |
| Number of pages | 9 |
| Journal | Current Psychiatry Reports |
| Volume | 8 |
| Issue number | 6 |
| DOIs | |
| State | Published - Dec 2006 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Psychiatry and Mental health
Cite this
New findings from the bipolar collaborative network : Clinical implications for therapeutics. / Post, Robert M.; Altshuler, Lori L.; Frye, Mark A; Suppes, Trisha; McElroy, Susan; Keck, Paul E.; Leverich, Gabriele S.; Kupka, Ralph; Nolen, Willem A.; Grunze, Heinz.
In: Current Psychiatry Reports, Vol. 8, No. 6, 12.2006, p. 489-497.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - New findings from the bipolar collaborative network
T2 - Clinical implications for therapeutics
AU - Post, Robert M.
AU - Altshuler, Lori L.
AU - Frye, Mark A
AU - Suppes, Trisha
AU - McElroy, Susan
AU - Keck, Paul E.
AU - Leverich, Gabriele S.
AU - Kupka, Ralph
AU - Nolen, Willem A.
AU - Grunze, Heinz
PY - 2006/12
Y1 - 2006/12
N2 - In this article, we highlight recent Bipolar Collaborative Network data. We found that childhood-onset bipolar illness is common, often goes untreated for more than a decade, and carries a poor prognosis. During randomized studies of adjunctive medications in depression: 1) Venlafaxine showed higher switch rates than bupropion or sertraline; 2) Tranylcypromine was as well tolerated as lamotrigine; and 3) Modafinil was more effective than placebo. Finally, in treatment of overweight and obesity, topiramate and sibutramine showed equal efficacy but poor tolerability, and zonisamide data showed that it may be useful for mood and weight loss.
AB - In this article, we highlight recent Bipolar Collaborative Network data. We found that childhood-onset bipolar illness is common, often goes untreated for more than a decade, and carries a poor prognosis. During randomized studies of adjunctive medications in depression: 1) Venlafaxine showed higher switch rates than bupropion or sertraline; 2) Tranylcypromine was as well tolerated as lamotrigine; and 3) Modafinil was more effective than placebo. Finally, in treatment of overweight and obesity, topiramate and sibutramine showed equal efficacy but poor tolerability, and zonisamide data showed that it may be useful for mood and weight loss.
UR - http://www.scopus.com/inward/record.url?scp=33845892528&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33845892528&partnerID=8YFLogxK
U2 - 10.1007/s11920-006-0056-5
DO - 10.1007/s11920-006-0056-5
M3 - Article
VL - 8
SP - 489
EP - 497
JO - Current Psychiatry Reports
JF - Current Psychiatry Reports
SN - 1523-3812
IS - 6
ER -