New esophageal function testing (impedance, Bravo pH monitoring, and high-resolution manometry): Clinical relevance

Jason A. Wilson, Marcelo F. Vela

Research output: Contribution to journalReview article

11 Scopus citations


Esophageal testing aims to quantify gastroesophageal reflux or characterize esophageal motility. Reflux monitoring traditionally has been based on the detection of acidic reflux by a transnasal catheter that measures esophageal pH. Recently there have been two major developments in this field: the wireless Bravo pH capsule (Medtronic, Inc., Minneapolis, MN), which allows catheter-free monitoring, and impedance-pH measurement, a catheter-based technique that enables detection of acidic and nonacidic reflux. The assessment of esophageal motility has relied on conventional manometry for many years. Two new proedures also recently became available to assess esophageal motility: high-resolution manometry, which uses many closely spaced pressure sensors and provides spatiotemporal plots of esophageal pressure changes, and impedance manometry, a test that directly measures bolus transit and provides conventional manometric data. The advantages, disadvantages, and clinical importance of these new esophageal tests are discussed in this review.

Original languageEnglish (US)
Pages (from-to)222-230
Number of pages9
JournalCurrent Gastroenterology Reports
Issue number3
StatePublished - 2008
Externally publishedYes

ASJC Scopus subject areas

  • Gastroenterology

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