New diagnosis of multiple myeloma in a patient with mantle cell lymphoma: Shared genetic factors or simple coincidence?

Mutende J. Sikuyayenga; Craig B. Reeder; Joseph R. Mikhael

doi:10.1016/j.lrr.2012.09.003

New diagnosis of multiple myeloma in a patient with mantle cell lymphoma: Shared genetic factors or simple coincidence?

Mutende J. Sikuyayenga, Craig B. Reeder, Joseph R. Mikhael

Hematology/Oncology

Research output: Contribution to journal › Article › peer-review

Abstract

Multiple Myeloma and Mantle Cell Lymphoma are well defined hematological malignancies. Understanding of their pathogeneses has led to new therapies and increased survival. We report on a 64-yr-old female who was diagnosed with mantle cell lymphoma in 2003, then multiple myeloma in 2010. We identified only few other cases of concomitant MM and MCL. We also explored the importance of t(11;14)(q13;q32). The development of these two disorders in the same patient may simply be due to chance; however, it may also represent a common genetic hit affecting the B-cell population leading to development of two different malignancies.

Original language	English (US)
Pages (from-to)	7-8
Number of pages	2
Journal	Leukemia Research Reports
Volume	1
Issue number	1
DOIs	https://doi.org/10.1016/j.lrr.2012.09.003
State	Published - 2012

Keywords

Mantle cell lymphoma
Multiple myeloma
T(11;14)(q13;q32)

ASJC Scopus subject areas

Hematology
Oncology

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10.1016/j.lrr.2012.09.003

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title = "New diagnosis of multiple myeloma in a patient with mantle cell lymphoma: Shared genetic factors or simple coincidence?",

abstract = "Multiple Myeloma and Mantle Cell Lymphoma are well defined hematological malignancies. Understanding of their pathogeneses has led to new therapies and increased survival. We report on a 64-yr-old female who was diagnosed with mantle cell lymphoma in 2003, then multiple myeloma in 2010. We identified only few other cases of concomitant MM and MCL. We also explored the importance of t(11;14)(q13;q32). The development of these two disorders in the same patient may simply be due to chance; however, it may also represent a common genetic hit affecting the B-cell population leading to development of two different malignancies.",

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T2 - Shared genetic factors or simple coincidence?

AU - Sikuyayenga, Mutende J.

AU - Reeder, Craig B.

AU - Mikhael, Joseph R.

PY - 2012

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AB - Multiple Myeloma and Mantle Cell Lymphoma are well defined hematological malignancies. Understanding of their pathogeneses has led to new therapies and increased survival. We report on a 64-yr-old female who was diagnosed with mantle cell lymphoma in 2003, then multiple myeloma in 2010. We identified only few other cases of concomitant MM and MCL. We also explored the importance of t(11;14)(q13;q32). The development of these two disorders in the same patient may simply be due to chance; however, it may also represent a common genetic hit affecting the B-cell population leading to development of two different malignancies.

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KW - Multiple myeloma

KW - T(11;14)(q13;q32)

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New diagnosis of multiple myeloma in a patient with mantle cell lymphoma: Shared genetic factors or simple coincidence?

Abstract

Keywords

ASJC Scopus subject areas

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