New diagnosis of multiple myeloma in a patient with mantle cell lymphoma: Shared genetic factors or simple coincidence?

Mutende J. Sikuyayenga, Craig B. Reeder, Joseph R. Mikhael

Research output: Contribution to journalArticle

Abstract

Multiple Myeloma and Mantle Cell Lymphoma are well defined hematological malignancies. Understanding of their pathogeneses has led to new therapies and increased survival. We report on a 64-yr-old female who was diagnosed with mantle cell lymphoma in 2003, then multiple myeloma in 2010. We identified only few other cases of concomitant MM and MCL. We also explored the importance of t(11;14)(q13;q32). The development of these two disorders in the same patient may simply be due to chance; however, it may also represent a common genetic hit affecting the B-cell population leading to development of two different malignancies.

Original languageEnglish (US)
Pages (from-to)7-8
Number of pages2
JournalLeukemia Research Reports
Volume1
Issue number1
DOIs
StatePublished - Dec 1 2012

Keywords

  • Mantle cell lymphoma
  • Multiple myeloma
  • T(11;14)(q13;q32)

ASJC Scopus subject areas

  • Hematology
  • Oncology

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