Neutrophil polycythemia rubra vera-1 expression in classic and atypical myeloproliferative disorders and laboratory correlates

Shireen Sirhan, Terra L. Lasho, Michelle A. Elliott, Ayalew Tefferi

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

The current study of 153 subjects with both classic and atypical myeloproliferative disorders suggests that neutrophil polycythemia rubra vera-1 (PRV-1) over-expression is a non-specific feature of clonal myeloproliferation that displays significant correlation with leukocyte alkaline phosphatase score. These observations undermine the utility of the PRV-1 assay as a diagnostic test of additional value.

Original languageEnglish (US)
Pages (from-to)406-408
Number of pages3
JournalHaematologica
Volume90
Issue number3
StatePublished - Mar 1 2005

Keywords

  • Diagnostic value
  • PRV-1
  • PRV-1 assay

ASJC Scopus subject areas

  • Hematology

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