Neutrophil polycythemia rubra vera-1 expression in classic and atypical myeloproliferative disorders and laboratory correlates

Shireen Sirhan, Terra L. Lasho, Michelle A. Elliott, Ayalew Tefferi

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The current study of 153 subjects with both classic and atypical myeloproliferative disorders suggests that neutrophil polycythemia rubra vera-1 (PRV-1) over-expression is a non-specific feature of clonal myeloproliferation that displays significant correlation with leukocyte alkaline phosphatase score. These observations undermine the utility of the PRV-1 assay as a diagnostic test of additional value.

Original languageEnglish (US)
Pages (from-to)406-408
Number of pages3
JournalHaematologica
Volume90
Issue number3
StatePublished - Mar 2005

Fingerprint

Myeloproliferative Disorders
Polycythemia Vera
Neutrophils
Routine Diagnostic Tests
Alkaline Phosphatase
Leukocytes

Keywords

  • Diagnostic value
  • PRV-1
  • PRV-1 assay

ASJC Scopus subject areas

  • Hematology

Cite this

Neutrophil polycythemia rubra vera-1 expression in classic and atypical myeloproliferative disorders and laboratory correlates. / Sirhan, Shireen; Lasho, Terra L.; Elliott, Michelle A.; Tefferi, Ayalew.

In: Haematologica, Vol. 90, No. 3, 03.2005, p. 406-408.

Research output: Contribution to journalArticle

@article{3a3e3a919afc4b679992e7b6270b9c51,
title = "Neutrophil polycythemia rubra vera-1 expression in classic and atypical myeloproliferative disorders and laboratory correlates",
abstract = "The current study of 153 subjects with both classic and atypical myeloproliferative disorders suggests that neutrophil polycythemia rubra vera-1 (PRV-1) over-expression is a non-specific feature of clonal myeloproliferation that displays significant correlation with leukocyte alkaline phosphatase score. These observations undermine the utility of the PRV-1 assay as a diagnostic test of additional value.",
keywords = "Diagnostic value, PRV-1, PRV-1 assay",
author = "Shireen Sirhan and Lasho, {Terra L.} and Elliott, {Michelle A.} and Ayalew Tefferi",
year = "2005",
month = "3",
language = "English (US)",
volume = "90",
pages = "406--408",
journal = "Haematologica",
issn = "0390-6078",
publisher = "Ferrata Storti Foundation",
number = "3",

}

TY - JOUR

T1 - Neutrophil polycythemia rubra vera-1 expression in classic and atypical myeloproliferative disorders and laboratory correlates

AU - Sirhan, Shireen

AU - Lasho, Terra L.

AU - Elliott, Michelle A.

AU - Tefferi, Ayalew

PY - 2005/3

Y1 - 2005/3

N2 - The current study of 153 subjects with both classic and atypical myeloproliferative disorders suggests that neutrophil polycythemia rubra vera-1 (PRV-1) over-expression is a non-specific feature of clonal myeloproliferation that displays significant correlation with leukocyte alkaline phosphatase score. These observations undermine the utility of the PRV-1 assay as a diagnostic test of additional value.

AB - The current study of 153 subjects with both classic and atypical myeloproliferative disorders suggests that neutrophil polycythemia rubra vera-1 (PRV-1) over-expression is a non-specific feature of clonal myeloproliferation that displays significant correlation with leukocyte alkaline phosphatase score. These observations undermine the utility of the PRV-1 assay as a diagnostic test of additional value.

KW - Diagnostic value

KW - PRV-1

KW - PRV-1 assay

UR - http://www.scopus.com/inward/record.url?scp=15244354382&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=15244354382&partnerID=8YFLogxK

M3 - Article

C2 - 15749676

AN - SCOPUS:15244354382

VL - 90

SP - 406

EP - 408

JO - Haematologica

JF - Haematologica

SN - 0390-6078

IS - 3

ER -