Neurotensin analogs indications for use as potential antipsychotic compounds

Beth M. McMahon, Mona Boules, Lewis Warrington, Elliott Richelson

Research output: Contribution to journalReview article

26 Scopus citations

Abstract

This review will be an update, focusing on the central nervous system (CNS) roles of the neurotransmitter, neurotensin. We will provide a summary of current knowledge about neurotensin, why it is an important peptide to study, and where the field is heading. Special emphasis is placed on the development of neurotensin analogs, which has been a major effort of our group, the potential role of neurotensin in Parkinson's disease, and the interaction of neurotensin with other neurotransmitters as evidenced by microdialysis studies.

Original languageEnglish (US)
Pages (from-to)1101-1119
Number of pages19
JournalLife Sciences
Volume70
Issue number10
DOIs
StatePublished - Jan 25 2002

Keywords

  • Antipsychotic
  • Central nervous system
  • Neurotensin
  • Neurotensin analogs

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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  • Cite this

    McMahon, B. M., Boules, M., Warrington, L., & Richelson, E. (2002). Neurotensin analogs indications for use as potential antipsychotic compounds. Life Sciences, 70(10), 1101-1119. https://doi.org/10.1016/S0024-3205(01)01520-X