Neurotensin agonists

Possible drugs for treatment of psychostimulant abuse

Elliott Richelson, Mona Boules, Paul Fredrickson

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Although many neuropeptides have been implicated in the pathophysiology of psychostimulant abuse, the tridecapeptide neurotensin holds a prominent position in this field due to the compelling literature on this peptide and psychostimulants. These data strongly support the hypothesis that a neurotensin agonist will be clinically useful to treat the abuse of psychostimulants, including nicotine. This paper reviews the evidence for a role for neurotensin in stimulant abuse and for a neurotensin agonist for its treatment.

Original languageEnglish (US)
Pages (from-to)679-690
Number of pages12
JournalLife Sciences
Volume73
Issue number6
DOIs
StatePublished - Jun 27 2003

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Neurotensin
Pharmaceutical Preparations
Neuropeptides
Nicotine
Peptides

ASJC Scopus subject areas

  • Pharmacology

Cite this

Neurotensin agonists : Possible drugs for treatment of psychostimulant abuse. / Richelson, Elliott; Boules, Mona; Fredrickson, Paul.

In: Life Sciences, Vol. 73, No. 6, 27.06.2003, p. 679-690.

Research output: Contribution to journalArticle

Richelson, Elliott ; Boules, Mona ; Fredrickson, Paul. / Neurotensin agonists : Possible drugs for treatment of psychostimulant abuse. In: Life Sciences. 2003 ; Vol. 73, No. 6. pp. 679-690.
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