Neuropsychologic performance among children in remission from acute lymphocytic leukemia

R. J. Ivnik, R. C. Colligan, S. W. Obetz, W. A. Smithson

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

Comprehensive neuropsychologic assessments were done for children in continuous remission from acute lymphocytic leukemia (ALL) following either chemotherapy alone (N=14) or chemotherapy combined with prophylactic cranial radiation (N=19). Only 5 of 75 neuropsychologic variables were found to differ at the .05 level for these two groups; trends were seen (p < .10) on two additional variables. The data indicate few if any meaningful differences related to the presence or absence of radiation therapy, although the differences that were seen occurred on tasks for which authors have suggested diminished ability as a result of cranial radiation. Additional analysis failed to reveal any effects related to the age at which prophylactic radiation was received.

Original languageEnglish (US)
Pages (from-to)29-34
Number of pages6
JournalJournal of Developmental and Behavioral Pediatrics
Volume2
Issue number2
StatePublished - 1981

Fingerprint

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Radiation
Drug Therapy
Radiotherapy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Behavioral Neuroscience
  • Psychology(all)
  • Developmental and Educational Psychology

Cite this

Neuropsychologic performance among children in remission from acute lymphocytic leukemia. / Ivnik, R. J.; Colligan, R. C.; Obetz, S. W.; Smithson, W. A.

In: Journal of Developmental and Behavioral Pediatrics, Vol. 2, No. 2, 1981, p. 29-34.

Research output: Contribution to journalArticle

Ivnik, R. J. ; Colligan, R. C. ; Obetz, S. W. ; Smithson, W. A. / Neuropsychologic performance among children in remission from acute lymphocytic leukemia. In: Journal of Developmental and Behavioral Pediatrics. 1981 ; Vol. 2, No. 2. pp. 29-34.
@article{9b364005d2594030b5b845ac7204e154,
title = "Neuropsychologic performance among children in remission from acute lymphocytic leukemia",
abstract = "Comprehensive neuropsychologic assessments were done for children in continuous remission from acute lymphocytic leukemia (ALL) following either chemotherapy alone (N=14) or chemotherapy combined with prophylactic cranial radiation (N=19). Only 5 of 75 neuropsychologic variables were found to differ at the .05 level for these two groups; trends were seen (p < .10) on two additional variables. The data indicate few if any meaningful differences related to the presence or absence of radiation therapy, although the differences that were seen occurred on tasks for which authors have suggested diminished ability as a result of cranial radiation. Additional analysis failed to reveal any effects related to the age at which prophylactic radiation was received.",
author = "Ivnik, {R. J.} and Colligan, {R. C.} and Obetz, {S. W.} and Smithson, {W. A.}",
year = "1981",
language = "English (US)",
volume = "2",
pages = "29--34",
journal = "Journal of Developmental and Behavioral Pediatrics",
issn = "0196-206X",
publisher = "Lippincott Williams and Wilkins",
number = "2",

}

TY - JOUR

T1 - Neuropsychologic performance among children in remission from acute lymphocytic leukemia

AU - Ivnik, R. J.

AU - Colligan, R. C.

AU - Obetz, S. W.

AU - Smithson, W. A.

PY - 1981

Y1 - 1981

N2 - Comprehensive neuropsychologic assessments were done for children in continuous remission from acute lymphocytic leukemia (ALL) following either chemotherapy alone (N=14) or chemotherapy combined with prophylactic cranial radiation (N=19). Only 5 of 75 neuropsychologic variables were found to differ at the .05 level for these two groups; trends were seen (p < .10) on two additional variables. The data indicate few if any meaningful differences related to the presence or absence of radiation therapy, although the differences that were seen occurred on tasks for which authors have suggested diminished ability as a result of cranial radiation. Additional analysis failed to reveal any effects related to the age at which prophylactic radiation was received.

AB - Comprehensive neuropsychologic assessments were done for children in continuous remission from acute lymphocytic leukemia (ALL) following either chemotherapy alone (N=14) or chemotherapy combined with prophylactic cranial radiation (N=19). Only 5 of 75 neuropsychologic variables were found to differ at the .05 level for these two groups; trends were seen (p < .10) on two additional variables. The data indicate few if any meaningful differences related to the presence or absence of radiation therapy, although the differences that were seen occurred on tasks for which authors have suggested diminished ability as a result of cranial radiation. Additional analysis failed to reveal any effects related to the age at which prophylactic radiation was received.

UR - http://www.scopus.com/inward/record.url?scp=0019719166&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019719166&partnerID=8YFLogxK

M3 - Article

C2 - 6943148

AN - SCOPUS:0019719166

VL - 2

SP - 29

EP - 34

JO - Journal of Developmental and Behavioral Pediatrics

JF - Journal of Developmental and Behavioral Pediatrics

SN - 0196-206X

IS - 2

ER -