Neuropathology of Alzheimer's disease and other dementias

Research output: Contribution to journalArticle

80 Citations (Scopus)

Abstract

Clinical differentiation of neurodegenerative diseases that produce dementia is imprecise. Neuropathology offers the only way to make a definite diagnosis. The CNS autopsy is also important for clinical quality control and for providing tissue that furthers research into these disabling disorders. This brief article summarizes the major neuropathologic features of largely sporadic disorders that present with late-life dementia. The common causes of dementia discussed are Alzheimer's disease, Lewy body disease, and vascular dementia; less common disorders described are dementia lacking distinctive histopathology, Pick's disease, progressive supranuclear palsy, corticobasal degeneration, and Creutzfeldt-Jakob disease.

Original languageEnglish (US)
Pages (from-to)209-228
Number of pages20
JournalClinics in Geriatric Medicine
Volume17
Issue number2
DOIs
StatePublished - 2001

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Dementia
Alzheimer Disease
Lewy Body Disease
Pick Disease of the Brain
Progressive Supranuclear Palsy
Creutzfeldt-Jakob Syndrome
Vascular Dementia
Neurodegenerative Diseases
Quality Control
Autopsy
Neuropathology
Research

ASJC Scopus subject areas

  • Geriatrics and Gerontology

Cite this

Neuropathology of Alzheimer's disease and other dementias. / Dickson, Dennis W.

In: Clinics in Geriatric Medicine, Vol. 17, No. 2, 2001, p. 209-228.

Research output: Contribution to journalArticle

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