Neuropathic Postural Tachycardia Syndrome

Research output: Chapter in Book/Report/Conference proceedingChapter


Postural tachycardia syndrome (POTS) is heterogeneous, presumably, autoimmune autonomic neuropathy. Compared with a healthy population, patients with POTS reported impairment in multiple domains of quality of life, including physical, social, and role functioning. A variety of approaches have been used to alleviate symptoms in POTS. All patients need volume expansion and a high-salt/high-fluid regimen. Drugs that seem to enjoy the greatest success are midodrine, propranolol, and fludrocortisone. Other measures used include body stockings and physical counter maneuvers. These treatments may influence pathophysiologic mechanisms of POTS, such as α-receptor dysfunction, β-receptor supersensitivity, venous pooling, and brainstem center dysfunction.

Original languageEnglish (US)
Title of host publicationPrimer on the Autonomic Nervous System: Second Edition
PublisherElsevier Inc.
Number of pages3
ISBN (Print)9780080473963, 9780125897624
StatePublished - May 5 2004

ASJC Scopus subject areas

  • Medicine(all)
  • Neuroscience(all)


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