Neuromyelitis optica spectrum disorders in children and adolescents

Silvia Tenembaum, Tanuja Chitnis, Ichiro Nakashima, Nicolas Collongues, Andrew B McKeon, Michael Levy, Kevin Rostasy

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36 Scopus citations

Abstract

Neuromyelitis optica (NMO) is a severe autoimmune disease of the CNS characterized by recurrent inflammatory events primarily involving the optic nerves and spinal cord.NMOis infrequent in children, but early recognition is important to start adequate treatment. In this article, we review the evolving diagnostic criteria of NMO and provide an update on the clinical and neuroimaging spectrum of the disorder in pediatric patients, including current knowledge on immunopathogenesis and treatment recommendations for children with NMO.

Original languageEnglish (US)
Pages (from-to)S59-S66
JournalNeurology
Volume87
Issue number9
DOIs
StatePublished - Aug 30 2016

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ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Tenembaum, S., Chitnis, T., Nakashima, I., Collongues, N., McKeon, A. B., Levy, M., & Rostasy, K. (2016). Neuromyelitis optica spectrum disorders in children and adolescents. Neurology, 87(9), S59-S66. https://doi.org/10.1212/WNL.0000000000002824