Neuromyelitis optica spectrum disorders in children and adolescents

Silvia Tenembaum; Tanuja Chitnis; Ichiro Nakashima; Nicolas Collongues; Andrew McKeon; Michael Levy; Kevin Rostasy

doi:10.1212/WNL.0000000000002824

Neuromyelitis optica spectrum disorders in children and adolescents

Silvia Tenembaum, Tanuja Chitnis, Ichiro Nakashima, Nicolas Collongues, Andrew McKeon, Michael Levy, Kevin Rostasy

Laboratory Medicine and Pathology

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

Neuromyelitis optica (NMO) is a severe autoimmune disease of the CNS characterized by recurrent inflammatory events primarily involving the optic nerves and spinal cord.NMOis infrequent in children, but early recognition is important to start adequate treatment. In this article, we review the evolving diagnostic criteria of NMO and provide an update on the clinical and neuroimaging spectrum of the disorder in pediatric patients, including current knowledge on immunopathogenesis and treatment recommendations for children with NMO.

Original language	English (US)
Pages (from-to)	S59-S66
Journal	Neurology
Volume	87
Issue number	9
DOIs	https://doi.org/10.1212/WNL.0000000000002824
State	Published - Aug 30 2016

ASJC Scopus subject areas

Clinical Neurology

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10.1212/WNL.0000000000002824

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AU - Tenembaum, Silvia

AU - Chitnis, Tanuja

AU - Nakashima, Ichiro

AU - Collongues, Nicolas

AU - McKeon, Andrew

AU - Levy, Michael

AU - Rostasy, Kevin

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AB - Neuromyelitis optica (NMO) is a severe autoimmune disease of the CNS characterized by recurrent inflammatory events primarily involving the optic nerves and spinal cord.NMOis infrequent in children, but early recognition is important to start adequate treatment. In this article, we review the evolving diagnostic criteria of NMO and provide an update on the clinical and neuroimaging spectrum of the disorder in pediatric patients, including current knowledge on immunopathogenesis and treatment recommendations for children with NMO.

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Neuromyelitis optica spectrum disorders in children and adolescents

Abstract

ASJC Scopus subject areas

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