TY - JOUR
T1 - Neuromuscular paraneoplastic syndromes
T2 - The Lambert-Eaton myasthenic syndrome
AU - Prommer, Eric
PY - 2010/9/1
Y1 - 2010/9/1
N2 - Background: Disorders in which the effects of cancer occur at a site remote from the primary tumor are termed paraneoplastic disorders. The most well-known paraneoplastic disorder affecting the neuromuscular junction is the Lambert-Eaton myasthenic syndrome (LEMS). Discussion: We describe a case of the Lambert-Eaton myasthenic syndrome diagnosed in a patient with small cell lung cancer presenting with profound weakness. The discussion that follows the case describes the pathophysiology of the disorder, clinical characteristics and therapies that have been used. The role of the palliative care team in the case is described.
AB - Background: Disorders in which the effects of cancer occur at a site remote from the primary tumor are termed paraneoplastic disorders. The most well-known paraneoplastic disorder affecting the neuromuscular junction is the Lambert-Eaton myasthenic syndrome (LEMS). Discussion: We describe a case of the Lambert-Eaton myasthenic syndrome diagnosed in a patient with small cell lung cancer presenting with profound weakness. The discussion that follows the case describes the pathophysiology of the disorder, clinical characteristics and therapies that have been used. The role of the palliative care team in the case is described.
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U2 - 10.1089/jpm.2009.0418
DO - 10.1089/jpm.2009.0418
M3 - Article
C2 - 20836646
AN - SCOPUS:77956587193
SN - 1096-6218
VL - 13
SP - 1159
EP - 1162
JO - Journal of Palliative Medicine
JF - Journal of Palliative Medicine
IS - 9
ER -