Neurological complications of plasma cell disorders

Jan Drappatz; Kurt A. Jaeckle

doi:10.1007/9781441976680_18

Neurological complications of plasma cell disorders

Jan Drappatz, Kurt A. Jaeckle

Neurology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Plasma cell disorders include monoclonal gammopathies of unknown significance, multiple myeloma, plasmacytoma, Waldenstrom's macroglobulinemia, and amyloidosis. This group of neoplastic diseases involves proliferation of a single clone of plasma cells, producing a monoclonal immunoglobulin protein or immunoglobulin fragment (M protein) that can be identified as a spike on electrophoresis of serum or urine. Plasma cell disorders are associated with a wide spectrum of neurological complications. The pathophysiology, diagnosis, and management of these neurological complications are the subject of this review.

Original language	English (US)
Title of host publication	Lymphoma and Leukemia of the Nervous System
Publisher	Springer New York
Pages	299-312
Number of pages	14
ISBN (Electronic)	9781441976680
ISBN (Print)	9781441976673
DOIs	https://doi.org/10.1007/9781441976680_18
State	Published - Jan 1 2012

ASJC Scopus subject areas

General Medicine

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10.1007/9781441976680_18

Cite this

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AB - Plasma cell disorders include monoclonal gammopathies of unknown significance, multiple myeloma, plasmacytoma, Waldenstrom's macroglobulinemia, and amyloidosis. This group of neoplastic diseases involves proliferation of a single clone of plasma cells, producing a monoclonal immunoglobulin protein or immunoglobulin fragment (M protein) that can be identified as a spike on electrophoresis of serum or urine. Plasma cell disorders are associated with a wide spectrum of neurological complications. The pathophysiology, diagnosis, and management of these neurological complications are the subject of this review.

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Neurological complications of plasma cell disorders

Abstract

ASJC Scopus subject areas

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