Neurological complications of plasma cell disorders

Jan Drappatz, Kurt A. Jaeckle

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Plasma cell disorders include monoclonal gammopathies of unknown significance, multiple myeloma, plasmacytoma, Waldenstrom's macroglobulinemia, and amyloidosis. This group of neoplastic diseases involves proliferation of a single clone of plasma cells, producing a monoclonal immunoglobulin protein or immunoglobulin fragment (M protein) that can be identified as a spike on electrophoresis of serum or urine. Plasma cell disorders are associated with a wide spectrum of neurological complications. The pathophysiology, diagnosis, and management of these neurological complications are the subject of this review.

Original languageEnglish (US)
Title of host publicationLymphoma and Leukemia of the Nervous System
PublisherSpringer New York
Pages299-312
Number of pages14
ISBN (Print)9781441976680, 9781441976673
DOIs
StatePublished - Jan 1 2012

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Drappatz, J., & Jaeckle, K. A. (2012). Neurological complications of plasma cell disorders. In Lymphoma and Leukemia of the Nervous System (pp. 299-312). Springer New York. https://doi.org/10.1007/9781441976680_18