Neurological complications of lymphomas

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

The neurologic complications of the malignant lymphomas are common, serious, and treatable. Some complications, such as dural involvement by MALT tumor and paraneoplastic ataxia of Hodgkin's disease, are unique to these malignancies. Compared to more common cancers the malignant lymphomas appear to affect the central and peripheral nervous systems disproportionately. As such they have the potential to significantly impact patients' quality of life because of effects on special senses, mobility, communication, and cognition. Because of the inextricable intersection with disordered immune system function, an additional challenge for the treating physician is determining whether the neurologic syndrome is due to cancer or to autoimmunity. The interplay between the two contribute to the morbidity and pose challenges to treatment. The potential for improvement validates an intensive review of these complications including new insights into pathogenesis, diagnosis, and treatment.

Original languageEnglish (US)
Title of host publicationCancer Neurology In Clinical Practice: Neurologic Complications of Cancer and Its Treatment: Second Edition
PublisherHumana Press
Pages567-589
Number of pages23
ISBN (Print)9781588299833
DOIs
StatePublished - 2008

Fingerprint

Lymphoma
Nervous System
Neoplasms
Peripheral Nervous System
Ataxia
Autoimmunity
Hodgkin Disease
Cognition
Immune System
Central Nervous System
Communication
Quality of Life
Morbidity
Physicians
Therapeutics

Keywords

  • Hodgkin's disease
  • lymphoma
  • neoplastic meningitis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

O'Neill, B. P. (2008). Neurological complications of lymphomas. In Cancer Neurology In Clinical Practice: Neurologic Complications of Cancer and Its Treatment: Second Edition (pp. 567-589). Humana Press. https://doi.org/10.1007/978-1-59745-412-4_30

Neurological complications of lymphomas. / O'Neill, Brian Patrick.

Cancer Neurology In Clinical Practice: Neurologic Complications of Cancer and Its Treatment: Second Edition. Humana Press, 2008. p. 567-589.

Research output: Chapter in Book/Report/Conference proceedingChapter

O'Neill, BP 2008, Neurological complications of lymphomas. in Cancer Neurology In Clinical Practice: Neurologic Complications of Cancer and Its Treatment: Second Edition. Humana Press, pp. 567-589. https://doi.org/10.1007/978-1-59745-412-4_30
O'Neill BP. Neurological complications of lymphomas. In Cancer Neurology In Clinical Practice: Neurologic Complications of Cancer and Its Treatment: Second Edition. Humana Press. 2008. p. 567-589 https://doi.org/10.1007/978-1-59745-412-4_30
O'Neill, Brian Patrick. / Neurological complications of lymphomas. Cancer Neurology In Clinical Practice: Neurologic Complications of Cancer and Its Treatment: Second Edition. Humana Press, 2008. pp. 567-589
@inbook{c46b79c7f047464194938f1c5ed8e183,
title = "Neurological complications of lymphomas",
abstract = "The neurologic complications of the malignant lymphomas are common, serious, and treatable. Some complications, such as dural involvement by MALT tumor and paraneoplastic ataxia of Hodgkin's disease, are unique to these malignancies. Compared to more common cancers the malignant lymphomas appear to affect the central and peripheral nervous systems disproportionately. As such they have the potential to significantly impact patients' quality of life because of effects on special senses, mobility, communication, and cognition. Because of the inextricable intersection with disordered immune system function, an additional challenge for the treating physician is determining whether the neurologic syndrome is due to cancer or to autoimmunity. The interplay between the two contribute to the morbidity and pose challenges to treatment. The potential for improvement validates an intensive review of these complications including new insights into pathogenesis, diagnosis, and treatment.",
keywords = "Hodgkin's disease, lymphoma, neoplastic meningitis",
author = "O'Neill, {Brian Patrick}",
year = "2008",
doi = "10.1007/978-1-59745-412-4_30",
language = "English (US)",
isbn = "9781588299833",
pages = "567--589",
booktitle = "Cancer Neurology In Clinical Practice: Neurologic Complications of Cancer and Its Treatment: Second Edition",
publisher = "Humana Press",

}

TY - CHAP

T1 - Neurological complications of lymphomas

AU - O'Neill, Brian Patrick

PY - 2008

Y1 - 2008

N2 - The neurologic complications of the malignant lymphomas are common, serious, and treatable. Some complications, such as dural involvement by MALT tumor and paraneoplastic ataxia of Hodgkin's disease, are unique to these malignancies. Compared to more common cancers the malignant lymphomas appear to affect the central and peripheral nervous systems disproportionately. As such they have the potential to significantly impact patients' quality of life because of effects on special senses, mobility, communication, and cognition. Because of the inextricable intersection with disordered immune system function, an additional challenge for the treating physician is determining whether the neurologic syndrome is due to cancer or to autoimmunity. The interplay between the two contribute to the morbidity and pose challenges to treatment. The potential for improvement validates an intensive review of these complications including new insights into pathogenesis, diagnosis, and treatment.

AB - The neurologic complications of the malignant lymphomas are common, serious, and treatable. Some complications, such as dural involvement by MALT tumor and paraneoplastic ataxia of Hodgkin's disease, are unique to these malignancies. Compared to more common cancers the malignant lymphomas appear to affect the central and peripheral nervous systems disproportionately. As such they have the potential to significantly impact patients' quality of life because of effects on special senses, mobility, communication, and cognition. Because of the inextricable intersection with disordered immune system function, an additional challenge for the treating physician is determining whether the neurologic syndrome is due to cancer or to autoimmunity. The interplay between the two contribute to the morbidity and pose challenges to treatment. The potential for improvement validates an intensive review of these complications including new insights into pathogenesis, diagnosis, and treatment.

KW - Hodgkin's disease

KW - lymphoma

KW - neoplastic meningitis

UR - http://www.scopus.com/inward/record.url?scp=84879434206&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84879434206&partnerID=8YFLogxK

U2 - 10.1007/978-1-59745-412-4_30

DO - 10.1007/978-1-59745-412-4_30

M3 - Chapter

SN - 9781588299833

SP - 567

EP - 589

BT - Cancer Neurology In Clinical Practice: Neurologic Complications of Cancer and Its Treatment: Second Edition

PB - Humana Press

ER -