Neurologic manifestations of podophyllin toxicity

C. M. Filley, Neill R Graff Radford, J. R. Lacy

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

A young woman presented with podophyllin intoxication following topical application of podophyllin resin to genital condylomata acuminata. The disorder was marked by hallucinatory psychosis, bone marrow depression, and mild hepatic dysfunction. The psychosis and systemic disturbances resolved within 3 weeks, but were followed by autonomic and sensorimotor peripheral neuropathy. This case illustrates the transient central neurotoxicity and persistent peripheral neurotoxicity of podophyllin.

Original languageEnglish (US)
Pages (from-to)308-311
Number of pages4
JournalNeurology
Volume32
Issue number3
StatePublished - 1982
Externally publishedYes

Fingerprint

Podophyllin
Neurologic Manifestations
Psychotic Disorders
Condylomata Acuminata
Peripheral Nervous System Diseases
Bone Marrow
Depression
Liver

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Filley, C. M., Graff Radford, N. R., & Lacy, J. R. (1982). Neurologic manifestations of podophyllin toxicity. Neurology, 32(3), 308-311.

Neurologic manifestations of podophyllin toxicity. / Filley, C. M.; Graff Radford, Neill R; Lacy, J. R.

In: Neurology, Vol. 32, No. 3, 1982, p. 308-311.

Research output: Contribution to journalArticle

Filley, CM, Graff Radford, NR & Lacy, JR 1982, 'Neurologic manifestations of podophyllin toxicity', Neurology, vol. 32, no. 3, pp. 308-311.
Filley, C. M. ; Graff Radford, Neill R ; Lacy, J. R. / Neurologic manifestations of podophyllin toxicity. In: Neurology. 1982 ; Vol. 32, No. 3. pp. 308-311.
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