Neurologic disease in biopsy-proven giant cell (temporal) arteritis

Richard John Caselli, G. G. Hunder, J. P. Whisnant

Research output: Contribution to journalArticlepeer-review

289 Scopus citations


Neurologic findings were studied in 166 consecutive patients with biopsy-proven giant cell (temporal) arteritis. Neurologic problems occurred in 51 patients (31%): neuropathies (23), TIA/strokes (12), neuro-otologic syndromes (11), tremor (6), neuropsychiatric syndromes (5), tongue numbness (3), and myelopathy (1). Neuro-ophthalmologic problems occurred in 35 patients (21%): amaurosis fugax (AF) (17), permanent vision loss (PVL) (14), scintillating scotoma (8), and diplopia (3). Abnormalities in large arteries in 52 patients (31%) included bruits and diminished pulses. The carotid artery was involved in 31 patients (bilateral in 58%). Overall, 35% of patients with carotid disease had TIA/stroke, AF, or PVL.

Original languageEnglish (US)
Pages (from-to)352-359
Number of pages8
Issue number3
StatePublished - 1988

ASJC Scopus subject areas

  • Neuroscience(all)

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