Neurologic complications of myeloma

Chafic Y. Karam; Michelle L. Mauermann

doi:10.1007/978-1-4614-8520-9_20

Neurologic complications of myeloma

Chafic Y. Karam, Michelle L. Mauermann

Neurology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Patients with multiple myeloma (MM) frequently develop neurological complications related to the disease or its treatment [ 1 – 3 ]. These neurological complications may affect the central nervous system (CNS) [ 4 ] or more commonly the peripheral nervous system (PNS) [ 1, 5 ]. Neurological complications can result from: (a) Direct infi ltration of the nervous system by neoplastic cells [ 4 ] (b) Indirect effect such as paraneoplastic syndrome or amyloid deposition [ 5 ] (c) Iatrogenic effect during multiple myeloma treatment [ 1 ] (d) Toxic-metabolic syndrome related to systemic complications of multiple myeloma [ 6 ] (e) A combination of the above Furthermore, a neurological syndrome can be the presenting sign of multiple myeloma [ 7 ]. In this chapter we will discuss these different neurological complications of myeloma by system (CNS vs. PNS) and the management of these complications (Table 20.1).

Original language	English (US)
Title of host publication	Multiple Myeloma
Subtitle of host publication	Diagnosis and Treatment
Publisher	Springer New York
Pages	245-256
Number of pages	12
ISBN (Electronic)	9781461485209
ISBN (Print)	9781461485193
DOIs	https://doi.org/10.1007/978-1-4614-8520-9_20
State	Published - Jan 1 2014

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1007/978-1-4614-8520-9_20

Cite this

@inbook{678f98086d1b403e9b2c4e8b998857ed,

title = "Neurologic complications of myeloma",

abstract = "Patients with multiple myeloma (MM) frequently develop neurological complications related to the disease or its treatment [ 1 – 3 ]. These neurological complications may affect the central nervous system (CNS) [ 4 ] or more commonly the peripheral nervous system (PNS) [ 1, 5 ]. Neurological complications can result from: (a) Direct infi ltration of the nervous system by neoplastic cells [ 4 ] (b) Indirect effect such as paraneoplastic syndrome or amyloid deposition [ 5 ] (c) Iatrogenic effect during multiple myeloma treatment [ 1 ] (d) Toxic-metabolic syndrome related to systemic complications of multiple myeloma [ 6 ] (e) A combination of the above Furthermore, a neurological syndrome can be the presenting sign of multiple myeloma [ 7 ]. In this chapter we will discuss these different neurological complications of myeloma by system (CNS vs. PNS) and the management of these complications (Table 20.1).",

author = "Karam, {Chafic Y.} and Mauermann, {Michelle L.}",

note = "Publisher Copyright: {\textcopyright} Mayo Foundation for Medical Education and Research 2014.",

year = "2014",

month = jan,

day = "1",

doi = "10.1007/978-1-4614-8520-9_20",

language = "English (US)",

isbn = "9781461485193",

pages = "245--256",

booktitle = "Multiple Myeloma",

publisher = "Springer New York",

}

TY - CHAP

T1 - Neurologic complications of myeloma

AU - Karam, Chafic Y.

AU - Mauermann, Michelle L.

N1 - Publisher Copyright: © Mayo Foundation for Medical Education and Research 2014.

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Patients with multiple myeloma (MM) frequently develop neurological complications related to the disease or its treatment [ 1 – 3 ]. These neurological complications may affect the central nervous system (CNS) [ 4 ] or more commonly the peripheral nervous system (PNS) [ 1, 5 ]. Neurological complications can result from: (a) Direct infi ltration of the nervous system by neoplastic cells [ 4 ] (b) Indirect effect such as paraneoplastic syndrome or amyloid deposition [ 5 ] (c) Iatrogenic effect during multiple myeloma treatment [ 1 ] (d) Toxic-metabolic syndrome related to systemic complications of multiple myeloma [ 6 ] (e) A combination of the above Furthermore, a neurological syndrome can be the presenting sign of multiple myeloma [ 7 ]. In this chapter we will discuss these different neurological complications of myeloma by system (CNS vs. PNS) and the management of these complications (Table 20.1).

AB - Patients with multiple myeloma (MM) frequently develop neurological complications related to the disease or its treatment [ 1 – 3 ]. These neurological complications may affect the central nervous system (CNS) [ 4 ] or more commonly the peripheral nervous system (PNS) [ 1, 5 ]. Neurological complications can result from: (a) Direct infi ltration of the nervous system by neoplastic cells [ 4 ] (b) Indirect effect such as paraneoplastic syndrome or amyloid deposition [ 5 ] (c) Iatrogenic effect during multiple myeloma treatment [ 1 ] (d) Toxic-metabolic syndrome related to systemic complications of multiple myeloma [ 6 ] (e) A combination of the above Furthermore, a neurological syndrome can be the presenting sign of multiple myeloma [ 7 ]. In this chapter we will discuss these different neurological complications of myeloma by system (CNS vs. PNS) and the management of these complications (Table 20.1).

UR - http://www.scopus.com/inward/record.url?scp=84956548799&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84956548799&partnerID=8YFLogxK

U2 - 10.1007/978-1-4614-8520-9_20

DO - 10.1007/978-1-4614-8520-9_20

M3 - Chapter

AN - SCOPUS:84956548799

SN - 9781461485193

SP - 245

EP - 256

BT - Multiple Myeloma

PB - Springer New York

ER -

Neurologic complications of myeloma

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this