Neurodegenerative diseases of Guam: Analysis of TAU

Jordi Pérez-Tur; L. Buée; H. R. Morris; S. C. Waring; L. Onstead; F. Wavrant-De Vrièze; R. Crook; V. Buée-Scherrer; P. R. Hof; R. C. Petersen; P. L. McGeer; A. Delacourte; M. Hutton; T. Siddique; J. E. Ahlskog; J. Hardy; J. C. Steele

doi:10.1212/wnl.53.2.411

Neurodegenerative diseases of Guam: Analysis of TAU

Jordi Pérez-Tur, L. Buée, H. R. Morris, S. C. Waring, L. Onstead, F. Wavrant-De Vrièze, R. Crook, V. Buée-Scherrer, P. R. Hof, R. C. Petersen, P. L. McGeer, A. Delacourte, M. Hutton, T. Siddique, J. E. Ahlskog, J. Hardy, J. C. Steele

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Abstract

Mutations in the tau gene have been described in families affected by frontotemporal dementia with parkinsonism linked to chromosome 17. The authors performed a genetic and biochemical analysis of this gene and its product in the parkinsonism dementia complex of Guam, a disorder characterized by the extensive formation of neurofibrillary tangles. The tau gene is not a primary cause of the parkinsonism dementia complex of Guam.

Original language	English (US)
Pages (from-to)	411-413
Number of pages	3
Journal	Neurology
Volume	53
Issue number	2
DOIs	https://doi.org/10.1212/wnl.53.2.411
State	Published - Jul 22 1999

ASJC Scopus subject areas

Clinical Neurology

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Pérez-Tur, J., Buée, L., Morris, H. R., Waring, S. C., Onstead, L., Wavrant-De Vrièze, F., Crook, R., Buée-Scherrer, V., Hof, P. R., Petersen, R. C., McGeer, P. L., Delacourte, A., Hutton, M., Siddique, T., Ahlskog, J. E., Hardy, J., & Steele, J. C. (1999). Neurodegenerative diseases of Guam: Analysis of TAU. Neurology, 53(2), 411-413. https://doi.org/10.1212/wnl.53.2.411

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abstract = "Mutations in the tau gene have been described in families affected by frontotemporal dementia with parkinsonism linked to chromosome 17. The authors performed a genetic and biochemical analysis of this gene and its product in the parkinsonism dementia complex of Guam, a disorder characterized by the extensive formation of neurofibrillary tangles. The tau gene is not a primary cause of the parkinsonism dementia complex of Guam.",

author = "Jordi P{\'e}rez-Tur and L. Bu{\'e}e and Morris, {H. R.} and Waring, {S. C.} and L. Onstead and {Wavrant-De Vri{\`e}ze}, F. and R. Crook and V. Bu{\'e}e-Scherrer and Hof, {P. R.} and Petersen, {R. C.} and McGeer, {P. L.} and A. Delacourte and M. Hutton and T. Siddique and Ahlskog, {J. E.} and J. Hardy and Steele, {J. C.}",

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T2 - Analysis of TAU

AU - Pérez-Tur, Jordi

AU - Buée, L.

AU - Morris, H. R.

AU - Waring, S. C.

AU - Onstead, L.

AU - Wavrant-De Vrièze, F.

AU - Crook, R.

AU - Buée-Scherrer, V.

AU - Hof, P. R.

AU - Petersen, R. C.

AU - McGeer, P. L.

AU - Delacourte, A.

AU - Hutton, M.

AU - Siddique, T.

AU - Ahlskog, J. E.

AU - Hardy, J.

AU - Steele, J. C.

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AB - Mutations in the tau gene have been described in families affected by frontotemporal dementia with parkinsonism linked to chromosome 17. The authors performed a genetic and biochemical analysis of this gene and its product in the parkinsonism dementia complex of Guam, a disorder characterized by the extensive formation of neurofibrillary tangles. The tau gene is not a primary cause of the parkinsonism dementia complex of Guam.

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Neurodegenerative diseases of Guam: Analysis of TAU

Abstract

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