Neurodegenerative diseases of Guam: Analysis of TAU

Jordi Pérez-Tur, L. Buée, H. R. Morris, S. C. Waring, L. Onstead, F. Wavrant-De Vrièze, R. Crook, V. Buée-Scherrer, P. R. Hof, R. C. Petersen, P. L. McGeer, A. Delacourte, M. Hutton, T. Siddique, J. E. Ahlskog, J. Hardy, J. C. Steele

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

Mutations in the tau gene have been described in families affected by frontotemporal dementia with parkinsonism linked to chromosome 17. The authors performed a genetic and biochemical analysis of this gene and its product in the parkinsonism dementia complex of Guam, a disorder characterized by the extensive formation of neurofibrillary tangles. The tau gene is not a primary cause of the parkinsonism dementia complex of Guam.

Original languageEnglish (US)
Pages (from-to)411-413
Number of pages3
JournalNeurology
Volume53
Issue number2
DOIs
StatePublished - Jul 22 1999

ASJC Scopus subject areas

  • Clinical Neurology

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  • Cite this

    Pérez-Tur, J., Buée, L., Morris, H. R., Waring, S. C., Onstead, L., Wavrant-De Vrièze, F., Crook, R., Buée-Scherrer, V., Hof, P. R., Petersen, R. C., McGeer, P. L., Delacourte, A., Hutton, M., Siddique, T., Ahlskog, J. E., Hardy, J., & Steele, J. C. (1999). Neurodegenerative diseases of Guam: Analysis of TAU. Neurology, 53(2), 411-413. https://doi.org/10.1212/wnl.53.2.411