Neurocognitive functioning and improvement in quality of life following participation in cardiac rehabilitation

Ronald A. Cohen, David J. Moser, Matthew M. Clark, Mark S. Aloia, Byron R. Cargill, Sandra Stefanik, Anna Albrecht, Peter Tilkemeier, Daniel E. Forman

Research output: Contribution to journalArticlepeer-review

89 Scopus citations


We investigated the relationship between neurocognitive functioning and quality of life/self-perceived health status (QOL) among cardiac rehabilitation (CR) patients to determine whether level of neurocognitive functioning is related to baseline QOL and improvement following CR. CR patients (n = 35) were given a neurocognitive screening before participation in CR, and also completed a behavioral inventory (SF-36) before and after CR to measure QOL associated with medical illness. At baseline, CR patients obtained relatively low SF-36 scores compared with published norms, and as reported previously, demonstrated inferior neurocognitive performance compared with healthy controls. Furthermore, neurocognitive performance was strongly positively correlated to SF-36 scores. Significant improvements were evident on many of the SF-36 subscales following rehabilitation. These improvements were relatively greater among SF-36 indexes of physical health status compared with SF-36 indexes of mental health status. Baseline neurocognitive performance also correlated strongly to the degree of improvement in SF-36 scores following rehabilitation. These findings indicate a strong relationship between baseline neurocognitive functioning and QOL before CR, and the degree to which QOL improves following this intervention.

Original languageEnglish (US)
Pages (from-to)1374-1378
Number of pages5
JournalAmerican Journal of Cardiology
Issue number9
StatePublished - May 1 1999

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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