NetPath: A public resource of curated signal transduction pathways

Kumaran Kandasamy, S. Sujatha Mohan, Rajesh Raju, Shivakumar Keerthikumar, Ghantasala S. Sameer Kumar, Abhilash K. Venugopal, Deepthi Telikicherla, Daniel J. Navarro, Suresh Mathivanan, Christian Pecquet, Sashi Kanth Gollapudi, Sudhir Gopal Tattikota, Shyam Mohan, Hariprasad Padhukasahasram, Yashwanth Subbannayya, Renu Goel, Harrys K.C. Jacob, Jun Zhong, Raja Sekhar, Vishalakshi NanjappaLavanya Balakrishnan, Roopashree Subbaiah, Y. L. Ramachandra, B. Abdul Rahiman, T. S. Keshava Prasad, Jian Xin Lin, Jon C.D. Houtman, Stephen Desiderio, Jean Christophe Renauld, Stefan Constantinescu, Osamu Ohara, Toshio Hirano, Masato Kubo, Sujay Singh, Purvesh Khatri, Sorin Draghici, Gary D. Bader, Chris Sander, Warren J. Leonard, Akhilesh Pandey

Research output: Contribution to journalArticle

245 Scopus citations

Abstract

We have developed NetPath as a resource of curated human signaling pathways. As an initial step, NetPath provides detailed maps of a number of immune signaling pathways, which include ~1,600 reactions annotated from the literature and more than 2,800 instances of transcriptionally-regulated genes - all linked to over 5,500 published articles. We anticipate NetPath to become a consolidated resource for human signaling pathways that should enable systems biology approaches.

Original languageEnglish (US)
Article numberr3
JournalGenome biology
Volume11
Issue number1
DOIs
StatePublished - Jan 12 2010

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ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Cell Biology

Cite this

Kandasamy, K., Sujatha Mohan, S., Raju, R., Keerthikumar, S., Sameer Kumar, G. S., Venugopal, A. K., Telikicherla, D., Navarro, D. J., Mathivanan, S., Pecquet, C., Gollapudi, S. K., Tattikota, S. G., Mohan, S., Padhukasahasram, H., Subbannayya, Y., Goel, R., Jacob, H. K. C., Zhong, J., Sekhar, R., ... Pandey, A. (2010). NetPath: A public resource of curated signal transduction pathways. Genome biology, 11(1), [r3]. https://doi.org/10.1186/gb-2010-11-1-r3