Nervous system involvement in SARS-coronavirus infection: a review on lessons learned from the previous outbreaks, ongoing pandemic and what to expect in the future

Atiq ur Rehman Bhatti, Jad Zreik, Yagiz Ugur Yolcu, Mohammed Ali Alvi, Kingsley Abode-Iyamah, Alfredo Quinones-Hinojosa, Mohamad Bydon

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Viral infections have been associated with the deleterious damage to nervous system resulting in impairment of the central nervous system as late sequalae infections. Since the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2), several studies have reported patients developing adverse neurological signs and symptoms. Like the outbreak of SARS in 2003, the recent outbreak has undermined the norm of the nervous system. This review will summarize the possible mechanism of neurological manifestations, the clinical presentations of patients with such symptoms secondary to SARS coronaviruses, and the prospective role of neurology and neurosurgery practice in managing these symptoms in the current climate.

Original languageEnglish (US)
Pages (from-to)930-938
Number of pages9
JournalInternational Journal of Neuroscience
Volume132
Issue number9
DOIs
StatePublished - 2022

Keywords

  • COVID-19
  • Nervous system
  • SARS-CoV2
  • coronavirus
  • neurological

ASJC Scopus subject areas

  • General Neuroscience

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