Nephrotic Syndrome

Bhavna Chopra; Leslie Thomas

doi:10.1016/j.ehmc.2013.11.008

Nephrotic Syndrome

Bhavna Chopra, Leslie Thomas

Nephrology

Research output: Contribution to journal › Review article › peer-review

Abstract

Minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), and membranous nephropathy (MN) are the most common causes of the nephrotic syndrome, diagnosed by demonstrating edema, proteinuria, hypoalbuminemia, and hyperlipidemia. MCD, FSGS, and MN vary by renal prognosis and known secondary causes. Renal biopsy is the gold standard for the proper diagnosis of MCD, FSGS, and MN. Management of the nephrotic syndrome is 2-fold: treatment of symptoms and complications (ie, edema, hyperlipidemia) and treatment of the underlying disease process (eg, corticosteroid therapy for primary diseases).

Original language	English (US)
Pages (from-to)	e245-e254
Journal	Hospital Medicine Clinics
Volume	3
Issue number	2
DOIs	https://doi.org/10.1016/j.ehmc.2013.11.008
State	Published - Apr 2014

Keywords

Edema
Focal segmental glomerulosclerosis
Membranous nephropathy
Minimal change disease
Nephrotic syndrome
Proteinuria

ASJC Scopus subject areas

General Medicine

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10.1016/j.ehmc.2013.11.008

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title = "Nephrotic Syndrome",

abstract = "Minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), and membranous nephropathy (MN) are the most common causes of the nephrotic syndrome, diagnosed by demonstrating edema, proteinuria, hypoalbuminemia, and hyperlipidemia. MCD, FSGS, and MN vary by renal prognosis and known secondary causes. Renal biopsy is the gold standard for the proper diagnosis of MCD, FSGS, and MN. Management of the nephrotic syndrome is 2-fold: treatment of symptoms and complications (ie, edema, hyperlipidemia) and treatment of the underlying disease process (eg, corticosteroid therapy for primary diseases).",

keywords = "Edema, Focal segmental glomerulosclerosis, Membranous nephropathy, Minimal change disease, Nephrotic syndrome, Proteinuria",

author = "Bhavna Chopra and Leslie Thomas",

year = "2014",

month = apr,

doi = "10.1016/j.ehmc.2013.11.008",

language = "English (US)",

volume = "3",

pages = "e245--e254",

journal = "Hospital Medicine Clinics",

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TY - JOUR

T1 - Nephrotic Syndrome

AU - Chopra, Bhavna

AU - Thomas, Leslie

PY - 2014/4

Y1 - 2014/4

N2 - Minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), and membranous nephropathy (MN) are the most common causes of the nephrotic syndrome, diagnosed by demonstrating edema, proteinuria, hypoalbuminemia, and hyperlipidemia. MCD, FSGS, and MN vary by renal prognosis and known secondary causes. Renal biopsy is the gold standard for the proper diagnosis of MCD, FSGS, and MN. Management of the nephrotic syndrome is 2-fold: treatment of symptoms and complications (ie, edema, hyperlipidemia) and treatment of the underlying disease process (eg, corticosteroid therapy for primary diseases).

AB - Minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), and membranous nephropathy (MN) are the most common causes of the nephrotic syndrome, diagnosed by demonstrating edema, proteinuria, hypoalbuminemia, and hyperlipidemia. MCD, FSGS, and MN vary by renal prognosis and known secondary causes. Renal biopsy is the gold standard for the proper diagnosis of MCD, FSGS, and MN. Management of the nephrotic syndrome is 2-fold: treatment of symptoms and complications (ie, edema, hyperlipidemia) and treatment of the underlying disease process (eg, corticosteroid therapy for primary diseases).

KW - Edema

KW - Focal segmental glomerulosclerosis

KW - Membranous nephropathy

KW - Minimal change disease

KW - Nephrotic syndrome

KW - Proteinuria

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U2 - 10.1016/j.ehmc.2013.11.008

DO - 10.1016/j.ehmc.2013.11.008

M3 - Review article

AN - SCOPUS:84897045856

SN - 2211-5943

VL - 3

SP - e245-e254

JO - Hospital Medicine Clinics

JF - Hospital Medicine Clinics

IS - 2

ER -

Nephrotic Syndrome

Abstract

Keywords

ASJC Scopus subject areas

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