Nephrogenic systemic fibrosis following acute kidney injury and exposure to gadolinium

Archana Bhaskaran, Purna Kashyap, Brent Kelly, Princy Ghera

Research output: Contribution to journalArticle

Abstract

Nephrogenic systemic fibrosis (NSF) is a scleroderma-like systemic fibrosing condition of unknown etiology described in patients with renal insufficiency. Gadolinium exposure has been strongly associated with the development of NSF though the mechanism of such injury is not known. There are only few reported cases of NSF in the setting of acute renal failure and fewer reported cases where skin lesions developed after kidney function had returned to normal. We report a case of NSF in a young Hispanic woman with lupus nephritis but normal creatinine, who received gadolinium during a brief episode of prerenal acute kidney injury not requiring dialysis, secondary to sepsis.

Original languageEnglish (US)
Pages (from-to)33-36
Number of pages4
JournalIndian Journal of Medical Sciences
Volume64
Issue number1
DOIs
StatePublished - Jan 1 2010

Keywords

  • Acute renal failure
  • gadolinium
  • nephrogenic systemic fibrosis
  • normal creatinine
  • normal kidney function
  • prerenal acute renal failure

ASJC Scopus subject areas

  • Medicine(all)

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