Neoplastic imitators of small bowel Crohn's disease

Andrew David Badley, R. E. MacCormick, G. P. LeBrun

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

To identify the problem of small bowel neoplasia masquerading as Crohn's disease. Data and methods: Sixteen articles reviewing the frequency of small bowel neoplasia were identified. Articles were selected if they assessed frequency of small bowel tumours in the general population. All articles were retrospective reviews of experience. Data on frequency were extracted and compiled. Three case reports as illustrative examples and a Medline search of small bowel neoplasms with manual searching of references from identified articles are presented. Results: A total of 2507 cases of small bowel tumours was compiled. The frequency of tumours in decreasing order was adenocarcinoma, carcinoid, lymphoma, leiomyoma, leiomyosarcoma, adenoma and lipoma. Conclusions: Crohn's disease is the most prevalent disease affecting terminal ileum. Malignant disease may affect the terminal small bowel in ways which are clinically indistinguishable from Crohn's disease. Surgery is the last therapeutic option for Crohn's disease, whereas it is potentially curative and therefore the first option for small bowel neoplasia. Misdiagnosing malignant processes as being Crohn's disease causes delays in effective treatment and worsens prognosis.

Original languageEnglish (US)
Pages (from-to)77-83
Number of pages7
JournalCanadian Journal of Gastroenterology
Volume6
Issue number2
StatePublished - 1992
Externally publishedYes

Fingerprint

Crohn Disease
Neoplasms
Leiomyosarcoma
Lipoma
Carcinoid Tumor
Leiomyoma
Diagnostic Errors
Ileum
Adenoma
Lymphoma
Adenocarcinoma
Population

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Neoplastic imitators of small bowel Crohn's disease. / Badley, Andrew David; MacCormick, R. E.; LeBrun, G. P.

In: Canadian Journal of Gastroenterology, Vol. 6, No. 2, 1992, p. 77-83.

Research output: Contribution to journalArticle

Badley, AD, MacCormick, RE & LeBrun, GP 1992, 'Neoplastic imitators of small bowel Crohn's disease', Canadian Journal of Gastroenterology, vol. 6, no. 2, pp. 77-83.
Badley, Andrew David ; MacCormick, R. E. ; LeBrun, G. P. / Neoplastic imitators of small bowel Crohn's disease. In: Canadian Journal of Gastroenterology. 1992 ; Vol. 6, No. 2. pp. 77-83.
@article{c4643b31da4b4701940b4755532e2e6a,
title = "Neoplastic imitators of small bowel Crohn's disease",
abstract = "To identify the problem of small bowel neoplasia masquerading as Crohn's disease. Data and methods: Sixteen articles reviewing the frequency of small bowel neoplasia were identified. Articles were selected if they assessed frequency of small bowel tumours in the general population. All articles were retrospective reviews of experience. Data on frequency were extracted and compiled. Three case reports as illustrative examples and a Medline search of small bowel neoplasms with manual searching of references from identified articles are presented. Results: A total of 2507 cases of small bowel tumours was compiled. The frequency of tumours in decreasing order was adenocarcinoma, carcinoid, lymphoma, leiomyoma, leiomyosarcoma, adenoma and lipoma. Conclusions: Crohn's disease is the most prevalent disease affecting terminal ileum. Malignant disease may affect the terminal small bowel in ways which are clinically indistinguishable from Crohn's disease. Surgery is the last therapeutic option for Crohn's disease, whereas it is potentially curative and therefore the first option for small bowel neoplasia. Misdiagnosing malignant processes as being Crohn's disease causes delays in effective treatment and worsens prognosis.",
author = "Badley, {Andrew David} and MacCormick, {R. E.} and LeBrun, {G. P.}",
year = "1992",
language = "English (US)",
volume = "6",
pages = "77--83",
journal = "Canadian Journal of Gastroenterology and Hepatology",
issn = "2291-2789",
publisher = "Pulsus Group Inc.",
number = "2",

}

TY - JOUR

T1 - Neoplastic imitators of small bowel Crohn's disease

AU - Badley, Andrew David

AU - MacCormick, R. E.

AU - LeBrun, G. P.

PY - 1992

Y1 - 1992

N2 - To identify the problem of small bowel neoplasia masquerading as Crohn's disease. Data and methods: Sixteen articles reviewing the frequency of small bowel neoplasia were identified. Articles were selected if they assessed frequency of small bowel tumours in the general population. All articles were retrospective reviews of experience. Data on frequency were extracted and compiled. Three case reports as illustrative examples and a Medline search of small bowel neoplasms with manual searching of references from identified articles are presented. Results: A total of 2507 cases of small bowel tumours was compiled. The frequency of tumours in decreasing order was adenocarcinoma, carcinoid, lymphoma, leiomyoma, leiomyosarcoma, adenoma and lipoma. Conclusions: Crohn's disease is the most prevalent disease affecting terminal ileum. Malignant disease may affect the terminal small bowel in ways which are clinically indistinguishable from Crohn's disease. Surgery is the last therapeutic option for Crohn's disease, whereas it is potentially curative and therefore the first option for small bowel neoplasia. Misdiagnosing malignant processes as being Crohn's disease causes delays in effective treatment and worsens prognosis.

AB - To identify the problem of small bowel neoplasia masquerading as Crohn's disease. Data and methods: Sixteen articles reviewing the frequency of small bowel neoplasia were identified. Articles were selected if they assessed frequency of small bowel tumours in the general population. All articles were retrospective reviews of experience. Data on frequency were extracted and compiled. Three case reports as illustrative examples and a Medline search of small bowel neoplasms with manual searching of references from identified articles are presented. Results: A total of 2507 cases of small bowel tumours was compiled. The frequency of tumours in decreasing order was adenocarcinoma, carcinoid, lymphoma, leiomyoma, leiomyosarcoma, adenoma and lipoma. Conclusions: Crohn's disease is the most prevalent disease affecting terminal ileum. Malignant disease may affect the terminal small bowel in ways which are clinically indistinguishable from Crohn's disease. Surgery is the last therapeutic option for Crohn's disease, whereas it is potentially curative and therefore the first option for small bowel neoplasia. Misdiagnosing malignant processes as being Crohn's disease causes delays in effective treatment and worsens prognosis.

UR - http://www.scopus.com/inward/record.url?scp=0026748267&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026748267&partnerID=8YFLogxK

M3 - Article

VL - 6

SP - 77

EP - 83

JO - Canadian Journal of Gastroenterology and Hepatology

JF - Canadian Journal of Gastroenterology and Hepatology

SN - 2291-2789

IS - 2

ER -