Necrotizing sarcoid granulomatosis: Computed tomography and pathologic findings

Objective: To describe the CT findings and corresponding pathological findings of necrotizing sarcoid granulomatosis (NSG). Materials and Methods: We reviewed the high-resolution CT and macroscopic and histologic findings in three pathologically proven cases of NSG. Results: The CT findings consisted of one case each with single nodule, multiple nodules, and parenchymal opacification. The abnormalities were peri-bronchovascular or subpleural in distribution. Histologically, all patients had sarcoid-like granulomas with central necrosis and granulomatous vasculitis. The CT findings correlated closely with the gross pathologic findings. Conclusion: We conclude that the CT manifestations of NSG reflect the variable macroscopic pathologic findings.