Natural killer cells.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

It is proposed that this article will encompass a review of primarily the human natural killer cell. The following parameters of the human natural killer (NK) cell will be reviewed: its ontogeny; surface membrane characteristics including monoclonal antibody reactivity, cell lineage, the natural killer sensitive targets, and the proposed mechanism of action of natural killer cells cytotoxicity against these NK sensitive targets; the status of natural killer cell in relationship to clinical disease; the alteration of natural killer cells both in vitro and in vivo; and finally postulate relevance of the natural killer cell in context of the evolution or pathophysiology of human disease. There will be an attempt through this review to encompass the more recent publications that pertain to the various sections.

Original languageEnglish (US)
Pages (from-to)343-359
Number of pages17
JournalCritical Reviews in Clinical Laboratory Sciences
Volume22
Issue number4
StatePublished - 1986
Externally publishedYes

Fingerprint

Natural Killer Cells
Cytotoxicity
Monoclonal Antibodies
Membranes
Cell Lineage

ASJC Scopus subject areas

  • Microbiology
  • Hematology
  • Immunology and Allergy
  • Pathology and Forensic Medicine
  • Radiology Nuclear Medicine and imaging
  • Biochemistry, medical
  • Biochemistry, Genetics and Molecular Biology(all)
  • Clinical Biochemistry

Cite this

Natural killer cells. / Kay, Neil Elliot.

In: Critical Reviews in Clinical Laboratory Sciences, Vol. 22, No. 4, 1986, p. 343-359.

Research output: Contribution to journalArticle

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