Natural history of headache five years after traumatic brain injury

Arthur Stacey, Sylvia Lucas, Sureyya Dikmen, Nancy Temkin, Kathleen R. Bell, Allen W Brown, Robert Brunner, Ramon Diaz-Arrastia, Thomas K. Watanabe, Alan Weintraub, Jeanne M. Hoffman

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Headache is one of the most frequently reported symptoms following traumatic brain injury (TBI). Little is known about how these headaches change over time. We describe the natural history of headache in individuals with moderate to severe TBI over 5 years after injury. A total of 316 patients were prospectively enrolled and followed at 3, 6, 12, and 60 months after injury. Individuals were 72% male, 73% white, and 55% injured in motor vehicle crashes, with an average age of 42. Pre-injury headache was reported in 17% of individuals. New or worse headache prevalence remained consistent with at least 33% at all time points. Incidence was >17% at all time points with first report of new or worse headache in 20% of participants at 60 months. Disability related to headache was high, with average headache pain (on 0-10 scale) ranging from 5.5 at baseline to 5.7 at 60 months post-injury, and reports of substantial impact on daily life across all time points. More than half of classifiable headaches matched the profile of migraine or probable migraine. Headache is a substantial problem after TBI. Results suggest that ongoing assessment and treatment of headache after TBI is needed, as this symptom may be a problem up to 5 years post-injury.

Original languageEnglish (US)
Pages (from-to)1558-1564
Number of pages7
JournalJournal of Neurotrauma
Volume34
Issue number8
DOIs
StatePublished - Apr 15 2017

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Headache
Wounds and Injuries
Migraine Disorders
Traumatic Brain Injury
Motor Vehicles
Pain
Incidence

Keywords

  • headache
  • post-traumatic headache
  • secondary headache
  • TBI

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Stacey, A., Lucas, S., Dikmen, S., Temkin, N., Bell, K. R., Brown, A. W., ... Hoffman, J. M. (2017). Natural history of headache five years after traumatic brain injury. Journal of Neurotrauma, 34(8), 1558-1564. https://doi.org/10.1089/neu.2016.4721

Natural history of headache five years after traumatic brain injury. / Stacey, Arthur; Lucas, Sylvia; Dikmen, Sureyya; Temkin, Nancy; Bell, Kathleen R.; Brown, Allen W; Brunner, Robert; Diaz-Arrastia, Ramon; Watanabe, Thomas K.; Weintraub, Alan; Hoffman, Jeanne M.

In: Journal of Neurotrauma, Vol. 34, No. 8, 15.04.2017, p. 1558-1564.

Research output: Contribution to journalArticle

Stacey, A, Lucas, S, Dikmen, S, Temkin, N, Bell, KR, Brown, AW, Brunner, R, Diaz-Arrastia, R, Watanabe, TK, Weintraub, A & Hoffman, JM 2017, 'Natural history of headache five years after traumatic brain injury', Journal of Neurotrauma, vol. 34, no. 8, pp. 1558-1564. https://doi.org/10.1089/neu.2016.4721
Stacey, Arthur ; Lucas, Sylvia ; Dikmen, Sureyya ; Temkin, Nancy ; Bell, Kathleen R. ; Brown, Allen W ; Brunner, Robert ; Diaz-Arrastia, Ramon ; Watanabe, Thomas K. ; Weintraub, Alan ; Hoffman, Jeanne M. / Natural history of headache five years after traumatic brain injury. In: Journal of Neurotrauma. 2017 ; Vol. 34, No. 8. pp. 1558-1564.
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