National Heart, Lung, and Blood Institute State of the Science Symposium in therapeutic apheresis - Therapeutic apheresis in cardiovascular disease

Jeffrey L. Winters; Leslie T. Cooper; Nora R. Ratcliffe; Yanyun Wu; Patrick M. Moriarty

doi:10.1002/jca.21355

National Heart, Lung, and Blood Institute State of the Science Symposium in therapeutic apheresis - Therapeutic apheresis in cardiovascular disease

Jeffrey L. Winters, Leslie T. Cooper, Nora R. Ratcliffe, Yanyun Wu, Patrick M. Moriarty

Cardiovascular Diseases

Research output: Contribution to journal › Comment/debate › peer-review

4 Scopus citations

Abstract

The National Heart, Lung, and Blood Institute in collaboration with the American Society for Apheresis, convened a State of the Science Symposium in November of 2012 due to the expanding application of therapeutic apheresis despite the lack of well-designed research to address its efficacy. This article reviews the opportunities that were presented at this meeting in the area of cardiovascular disease (CVD), specifically the use of columns to adsorb autoantibodies in dilated cardiomyopathy or damaging lipids in peripheral vascular disease. Understanding how absorption of these pathologic substances alters the inflammatory response in these disorders is important for the application of these technologies to the treatment of CVD.

Original language	English (US)
Pages (from-to)	183-187
Number of pages	5
Journal	Journal of Clinical Apheresis
Volume	30
Issue number	3
DOIs	https://doi.org/10.1002/jca.21355
State	Published - Jun 1 2015

Keywords

Apheresis
Immunoadsorption
Lipid apheresis
Myocarditis
Peripheral vascular disease

ASJC Scopus subject areas

Hematology

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10.1002/jca.21355

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title = "National Heart, Lung, and Blood Institute State of the Science Symposium in therapeutic apheresis - Therapeutic apheresis in cardiovascular disease",

abstract = "The National Heart, Lung, and Blood Institute in collaboration with the American Society for Apheresis, convened a State of the Science Symposium in November of 2012 due to the expanding application of therapeutic apheresis despite the lack of well-designed research to address its efficacy. This article reviews the opportunities that were presented at this meeting in the area of cardiovascular disease (CVD), specifically the use of columns to adsorb autoantibodies in dilated cardiomyopathy or damaging lipids in peripheral vascular disease. Understanding how absorption of these pathologic substances alters the inflammatory response in these disorders is important for the application of these technologies to the treatment of CVD.",

keywords = "Apheresis, Immunoadsorption, Lipid apheresis, Myocarditis, Peripheral vascular disease",

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AU - Winters, Jeffrey L.

AU - Cooper, Leslie T.

AU - Ratcliffe, Nora R.

AU - Wu, Yanyun

AU - Moriarty, Patrick M.

PY - 2015/6/1

Y1 - 2015/6/1

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AB - The National Heart, Lung, and Blood Institute in collaboration with the American Society for Apheresis, convened a State of the Science Symposium in November of 2012 due to the expanding application of therapeutic apheresis despite the lack of well-designed research to address its efficacy. This article reviews the opportunities that were presented at this meeting in the area of cardiovascular disease (CVD), specifically the use of columns to adsorb autoantibodies in dilated cardiomyopathy or damaging lipids in peripheral vascular disease. Understanding how absorption of these pathologic substances alters the inflammatory response in these disorders is important for the application of these technologies to the treatment of CVD.

KW - Apheresis

KW - Immunoadsorption

KW - Lipid apheresis

KW - Myocarditis

KW - Peripheral vascular disease

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National Heart, Lung, and Blood Institute State of the Science Symposium in therapeutic apheresis - Therapeutic apheresis in cardiovascular disease

Abstract

Keywords

ASJC Scopus subject areas

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