Nanoparticles and the lung: Friend or foe?

Y. S. Prakash, Sadis Matalon

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Nanomedicine is a rapidly evolving field with high potential for developing novel research, diagnosis, and/or therapeutic approaches for lung diseases. However, for engineered nanomaterials to reach their true potential, there are still a number of unanswered questions regarding nanomaterial vs. tissue properties that dictate lung cellular uptake, distribution, and intracellular effects, and particle vs. tissue factors that determine toxicity vs. beneficial effects in the lung. Some of these key questions are highlighted in this Perspectives. Addressing these important issues will help improve nanoparticle design and enhance enthusiasm for more widespread use of nanotechnology in pulmonary medicine.

Original languageEnglish (US)
Pages (from-to)L393-L396
JournalAmerican Journal of Physiology - Lung Cellular and Molecular Physiology
Volume306
Issue number5
DOIs
StatePublished - Mar 1 2014

ASJC Scopus subject areas

  • Physiology
  • Pulmonary and Respiratory Medicine
  • Physiology (medical)
  • Cell Biology

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