TY - JOUR
T1 - Myxoid hepatocellular neoplasms
T2 - imaging appearance of a unique mucinous tumor variant
AU - Young, Jesse T.
AU - Kurup, Anil N.
AU - Graham, Rondell P.
AU - Torbenson, Michael S.
AU - Venkatesh, Sudhakar K.
N1 - Publisher Copyright:
© 2016, Springer Science+Business Media New York.
PY - 2016/11/1
Y1 - 2016/11/1
N2 - Purpose: To describe the imaging appearance of myxoid hepatocellular neoplasms (MHNs), including adenomas and carcinomas, a recently described pathologically unique tumor variant. Materials and Methods: Single-institution review of pathologically proven MHNs revealed 4 patients with imaging prior to resection. All available cross-sectional imaging was then retrospectively reviewed in consensus using specified descriptive characteristics previously published for hepatocellular adenoma subtypes. Imaging characteristics on magnetic resonance imaging (MRI), ultrasound (US), and computed tomography (CT) were reviewed. Results: MHNs were predominantly markedly T2 hyperintense with thin internal septations, circumscribed with lobulated margins, and demonstrated heterogeneous enhancement on arterial phase that became more homogenous on delayed phases. The lesions were hypodense on CT with similar enhancement characteristics as on MRI. On US, they were mildly hyperechoic and heterogeneous with posterior acoustic enhancement. Conclusion: MHNs show distinct imaging features that may allow accurate noninvasive diagnosis and differentiation from other hepatic lesions, including cavernous hemangioma, focal nodular hyperplasia, and other variants of hepatocellular adenoma or carcinoma.
AB - Purpose: To describe the imaging appearance of myxoid hepatocellular neoplasms (MHNs), including adenomas and carcinomas, a recently described pathologically unique tumor variant. Materials and Methods: Single-institution review of pathologically proven MHNs revealed 4 patients with imaging prior to resection. All available cross-sectional imaging was then retrospectively reviewed in consensus using specified descriptive characteristics previously published for hepatocellular adenoma subtypes. Imaging characteristics on magnetic resonance imaging (MRI), ultrasound (US), and computed tomography (CT) were reviewed. Results: MHNs were predominantly markedly T2 hyperintense with thin internal septations, circumscribed with lobulated margins, and demonstrated heterogeneous enhancement on arterial phase that became more homogenous on delayed phases. The lesions were hypodense on CT with similar enhancement characteristics as on MRI. On US, they were mildly hyperechoic and heterogeneous with posterior acoustic enhancement. Conclusion: MHNs show distinct imaging features that may allow accurate noninvasive diagnosis and differentiation from other hepatic lesions, including cavernous hemangioma, focal nodular hyperplasia, and other variants of hepatocellular adenoma or carcinoma.
KW - CT
KW - Hepatic adenoma
KW - Hepatocellular carcinoma
KW - MRI
KW - Myxoid hepatocellular lesion
KW - Ultrasound
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U2 - 10.1007/s00261-016-0812-x
DO - 10.1007/s00261-016-0812-x
M3 - Article
C2 - 27334021
AN - SCOPUS:84975502908
SN - 2366-004X
VL - 41
SP - 2115
EP - 2122
JO - Abdominal Radiology
JF - Abdominal Radiology
IS - 11
ER -