Myotonic dystrophy type 2 with focal asymmetric muscle weakness and no electrical myotonia

Margherita Milone, Sat D. Batish, Jasper R. Daube

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Genetically proven myotonic dystrophy type 2 (DM2) was found in a 61-year-old woman with creatine kinase (CK) elevation and only isolated weakness of one triceps. There was no clinical or electrical myotonia. Electromyography (EMG) showed only scattered fibrillation potentials and short duration motor unit potentials. Muscle biopsy showed nonspecific myopathic features and highly atrophic fibers with nuclear clumps. DM2 should be considered in patients with focal proximal weakness and abnormal EMG without myotonic discharges.

Original languageEnglish (US)
Pages (from-to)383-385
Number of pages3
JournalMuscle and Nerve
Volume39
Issue number3
DOIs
StatePublished - Mar 2009

Fingerprint

Myotonia
Myotonic Dystrophy
Muscle Weakness
Electromyography
Creatine Kinase
Biopsy
Muscles

Keywords

  • Focal weakness
  • Myotonia
  • Myotonic dystrophy type 2

ASJC Scopus subject areas

  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)
  • Physiology

Cite this

Myotonic dystrophy type 2 with focal asymmetric muscle weakness and no electrical myotonia. / Milone, Margherita; Batish, Sat D.; Daube, Jasper R.

In: Muscle and Nerve, Vol. 39, No. 3, 03.2009, p. 383-385.

Research output: Contribution to journalArticle

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