Myocardial viability independently influences left ventricular diastolic function in the early phase after acute myocardial infarction

Andrea Rossi, Mariantonietta Cicoira, Maurizio Anselmi, Giorgio Golia, Loredana Latina, Monica Tinto, Piero Zardini, Jae Kuen Oh

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background: After acute myocardial infarction, a broad range of left ventricular (LV) end-diastolic pressure (LVEDP) is expected because of chamber remodeling. However, intrinsic characteristics of the infarcted tissue (necrosis or viability) may also play a role. We aimed to evaluate whether myocardial viability (Mviab) has an influence on LVEDP. Methods: One hundred twenty-three consecutive patients with acute myocardial infarction underwent low-dose dobutamine echocardiography (5-10 μg/kg/min) to assess Mviab. Mviab was quantitatively evaluated by the variation of Δ wall motion score index. Patients underwent left heart catheterization with recording of LVEDP and a complete echocardiographic examination with measurement of LV volumes, ejection fraction, and mass. Results: The overall population (81% male; mean age 58 ± 10 years) was divided into 2 groups according to the presence (group 1; 66 patients) or absence (group 2; 57 patients) of Mviab. LVEDP was higher in patients without Mviab (16 ± 8 vs 20 ± 7 mm Hg; P = .02). The multivariate analysis showed that A wall motion score index correlated with LVEDP (P = .01) independent of wall motion score index and LV end-systolic volume. Conclusions: After acute myocardial infarction, LVEDP shows wide variability and is independently associated with Mviab.

Original languageEnglish (US)
Pages (from-to)1490-1495
Number of pages6
JournalJournal of the American Society of Echocardiography
Volume15
Issue number12
DOIs
StatePublished - Dec 1 2002

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Left Ventricular Function
Myocardial Infarction
Blood Pressure
Stroke Volume
Dobutamine
Cardiac Catheterization
Echocardiography
Necrosis
Multivariate Analysis
Population

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

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Myocardial viability independently influences left ventricular diastolic function in the early phase after acute myocardial infarction. / Rossi, Andrea; Cicoira, Mariantonietta; Anselmi, Maurizio; Golia, Giorgio; Latina, Loredana; Tinto, Monica; Zardini, Piero; Oh, Jae Kuen.

In: Journal of the American Society of Echocardiography, Vol. 15, No. 12, 01.12.2002, p. 1490-1495.

Research output: Contribution to journalArticle

Rossi, Andrea ; Cicoira, Mariantonietta ; Anselmi, Maurizio ; Golia, Giorgio ; Latina, Loredana ; Tinto, Monica ; Zardini, Piero ; Oh, Jae Kuen. / Myocardial viability independently influences left ventricular diastolic function in the early phase after acute myocardial infarction. In: Journal of the American Society of Echocardiography. 2002 ; Vol. 15, No. 12. pp. 1490-1495.
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AU - Anselmi, Maurizio

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AU - Latina, Loredana

AU - Tinto, Monica

AU - Zardini, Piero

AU - Oh, Jae Kuen

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