TY - JOUR
T1 - Myocardial microcirculation as evaluated with CT
AU - Wu, X. S.
AU - Bahn, R. C.
AU - Ritman, E. L.
AU - Beyar, R.
AU - Sideman, S.
AU - Vatner, S.
AU - Arts, T.
AU - Akselrod, S.
AU - Lab, M.
AU - Bassingthwaighte, J.
AU - Lanir, Y.
AU - Ter Keurs, H. E.D.J.
PY - 1995
Y1 - 1995
N2 - This study explores use of whole-body CT imaging to separately quantitate the physiological behavior of the nonrecruitable (e.g., arterioles) and recruitable (mostly capillary) components of the intramyocardial microcirculation. In two groups of dogs, one with microembolization and one with epicardial artery stenosis, we demonstrate that intramyocardial blood volume (ρ) and blood flow (F) follow the relationship ρ = AF + BF( 1/2 ) where A represents the transit time of the recruitable and BF(- 1/2 ) is the transit time of the nonrecruitable components. These transit times are shown to change in different, but characteristic, patterns.
AB - This study explores use of whole-body CT imaging to separately quantitate the physiological behavior of the nonrecruitable (e.g., arterioles) and recruitable (mostly capillary) components of the intramyocardial microcirculation. In two groups of dogs, one with microembolization and one with epicardial artery stenosis, we demonstrate that intramyocardial blood volume (ρ) and blood flow (F) follow the relationship ρ = AF + BF( 1/2 ) where A represents the transit time of the recruitable and BF(- 1/2 ) is the transit time of the nonrecruitable components. These transit times are shown to change in different, but characteristic, patterns.
UR - http://www.scopus.com/inward/record.url?scp=0029119490&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029119490&partnerID=8YFLogxK
U2 - 10.1007/978-1-4615-1893-8_26
DO - 10.1007/978-1-4615-1893-8_26
M3 - Article
C2 - 8540403
AN - SCOPUS:0029119490
SN - 0065-2598
VL - 382
SP - 261
EP - 268
JO - Advances in experimental medicine and biology
JF - Advances in experimental medicine and biology
ER -