Recent experiments have demonstrated that regional myocardial ischemia develops in fibrillating hearts distal to a critical coronary stenosis (CS) during normothermic cardiopulmonary bypass. Possible mechanisms involved in the development of fibrillation induced ischemia distal to a CS are (1) higher oxygen demands compared to the beating nonworking heart, and (2) continuous high intramyocardial pressures during fibrillation which impede subendocardial blood flow. The present study was designed to test the hypothesis that converting fibrillating hearts to the beating nonworking state reduces regional myocardial ischemia distal to a critical coronary stenosis.
|Original language||English (US)|
|Number of pages||3|
|State||Published - 1976|
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