Myocardial infarction after hip fracture repair: A population-based study

Jeanne M. Huddleston, Rachel E. Gullerud, Fantley Smither, Paul M. Huddleston, Dirk R. Larson, Michael P. Phy, L. Joseph Melton, Veronique Lee Roger

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Objectives To quantify the occurrence of myocardial infarction (MI) occurring in the early postoperative period after surgical hip fracture repair and estimate the effect on 1-year mortality. Design A population-based, historical cohort study of individuals who underwent surgical repair of a hip fracture that used the computerized medical record linkage system of the Rochester Epidemiology Project. Setting Academic and community hospitals, outpatient offices, and nursing homes in Olmsted County, Minnesota. Participants Over the 15-year study period (1988-2002), 1,116 elderly adults underwent surgical repair of a hip fracture. Measurements At the end of the first 7 days after hip fracture repair, participants were classified into one of three groups: clinically verified MI (cv-MI), subclinical myocardial ischemia, and no myocardial ischemia. One-year mortality was compared between these groups. Multivariate models assessed risk factors for early postoperative cv-MI and 1-year mortality. Results Within the first 7 days after hip fracture repair, 116 (10.4%) participants experienced cv-MI and 41 (3.7%) subclinical myocardial ischemia. Overall 1-year mortality was 22%, with no difference between those with subclinical myocardial ischemia and those with no myocardial ischemia. One-year mortality for those with cv-MI (35.8%) was significantly higher than for the other two groups. Occurrence of early postoperative cv-MI, male sex, and history of heart failure or dementia were independently associated with greater 1-year mortality, whereas prefracture home residence and preoperative higher hemoglobin were protective. Conclusion Rates of early postoperative, cv-MI after hip fracture repair exceed rates after other major orthopedic surgeries and are independently associated with greater 1-year mortality.

Original languageEnglish (US)
Pages (from-to)2020-2026
Number of pages7
JournalJournal of the American Geriatrics Society
Volume60
Issue number11
DOIs
StatePublished - Nov 2012

Fingerprint

Hip Fractures
Myocardial Infarction
Myocardial Ischemia
Mortality
Population
Office Nursing
Medical Record Linkage
Computerized Medical Records Systems
Community Hospital
Nursing Homes
Postoperative Period
Orthopedics
Dementia
Hemoglobins
Epidemiology
Cohort Studies
Outpatients
Heart Failure

Keywords

  • geriatric
  • hip fracture
  • mortality
  • myocardial infarction
  • postoperative complications

ASJC Scopus subject areas

  • Geriatrics and Gerontology

Cite this

Huddleston, J. M., Gullerud, R. E., Smither, F., Huddleston, P. M., Larson, D. R., Phy, M. P., ... Roger, V. L. (2012). Myocardial infarction after hip fracture repair: A population-based study. Journal of the American Geriatrics Society, 60(11), 2020-2026. https://doi.org/10.1111/j.1532-5415.2012.04205.x

Myocardial infarction after hip fracture repair : A population-based study. / Huddleston, Jeanne M.; Gullerud, Rachel E.; Smither, Fantley; Huddleston, Paul M.; Larson, Dirk R.; Phy, Michael P.; Melton, L. Joseph; Roger, Veronique Lee.

In: Journal of the American Geriatrics Society, Vol. 60, No. 11, 11.2012, p. 2020-2026.

Research output: Contribution to journalArticle

Huddleston, JM, Gullerud, RE, Smither, F, Huddleston, PM, Larson, DR, Phy, MP, Melton, LJ & Roger, VL 2012, 'Myocardial infarction after hip fracture repair: A population-based study', Journal of the American Geriatrics Society, vol. 60, no. 11, pp. 2020-2026. https://doi.org/10.1111/j.1532-5415.2012.04205.x
Huddleston JM, Gullerud RE, Smither F, Huddleston PM, Larson DR, Phy MP et al. Myocardial infarction after hip fracture repair: A population-based study. Journal of the American Geriatrics Society. 2012 Nov;60(11):2020-2026. https://doi.org/10.1111/j.1532-5415.2012.04205.x
Huddleston, Jeanne M. ; Gullerud, Rachel E. ; Smither, Fantley ; Huddleston, Paul M. ; Larson, Dirk R. ; Phy, Michael P. ; Melton, L. Joseph ; Roger, Veronique Lee. / Myocardial infarction after hip fracture repair : A population-based study. In: Journal of the American Geriatrics Society. 2012 ; Vol. 60, No. 11. pp. 2020-2026.
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abstract = "Objectives To quantify the occurrence of myocardial infarction (MI) occurring in the early postoperative period after surgical hip fracture repair and estimate the effect on 1-year mortality. Design A population-based, historical cohort study of individuals who underwent surgical repair of a hip fracture that used the computerized medical record linkage system of the Rochester Epidemiology Project. Setting Academic and community hospitals, outpatient offices, and nursing homes in Olmsted County, Minnesota. Participants Over the 15-year study period (1988-2002), 1,116 elderly adults underwent surgical repair of a hip fracture. Measurements At the end of the first 7 days after hip fracture repair, participants were classified into one of three groups: clinically verified MI (cv-MI), subclinical myocardial ischemia, and no myocardial ischemia. One-year mortality was compared between these groups. Multivariate models assessed risk factors for early postoperative cv-MI and 1-year mortality. Results Within the first 7 days after hip fracture repair, 116 (10.4{\%}) participants experienced cv-MI and 41 (3.7{\%}) subclinical myocardial ischemia. Overall 1-year mortality was 22{\%}, with no difference between those with subclinical myocardial ischemia and those with no myocardial ischemia. One-year mortality for those with cv-MI (35.8{\%}) was significantly higher than for the other two groups. Occurrence of early postoperative cv-MI, male sex, and history of heart failure or dementia were independently associated with greater 1-year mortality, whereas prefracture home residence and preoperative higher hemoglobin were protective. Conclusion Rates of early postoperative, cv-MI after hip fracture repair exceed rates after other major orthopedic surgeries and are independently associated with greater 1-year mortality.",
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AU - Larson, Dirk R.

AU - Phy, Michael P.

AU - Melton, L. Joseph

AU - Roger, Veronique Lee

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N2 - Objectives To quantify the occurrence of myocardial infarction (MI) occurring in the early postoperative period after surgical hip fracture repair and estimate the effect on 1-year mortality. Design A population-based, historical cohort study of individuals who underwent surgical repair of a hip fracture that used the computerized medical record linkage system of the Rochester Epidemiology Project. Setting Academic and community hospitals, outpatient offices, and nursing homes in Olmsted County, Minnesota. Participants Over the 15-year study period (1988-2002), 1,116 elderly adults underwent surgical repair of a hip fracture. Measurements At the end of the first 7 days after hip fracture repair, participants were classified into one of three groups: clinically verified MI (cv-MI), subclinical myocardial ischemia, and no myocardial ischemia. One-year mortality was compared between these groups. Multivariate models assessed risk factors for early postoperative cv-MI and 1-year mortality. Results Within the first 7 days after hip fracture repair, 116 (10.4%) participants experienced cv-MI and 41 (3.7%) subclinical myocardial ischemia. Overall 1-year mortality was 22%, with no difference between those with subclinical myocardial ischemia and those with no myocardial ischemia. One-year mortality for those with cv-MI (35.8%) was significantly higher than for the other two groups. Occurrence of early postoperative cv-MI, male sex, and history of heart failure or dementia were independently associated with greater 1-year mortality, whereas prefracture home residence and preoperative higher hemoglobin were protective. Conclusion Rates of early postoperative, cv-MI after hip fracture repair exceed rates after other major orthopedic surgeries and are independently associated with greater 1-year mortality.

AB - Objectives To quantify the occurrence of myocardial infarction (MI) occurring in the early postoperative period after surgical hip fracture repair and estimate the effect on 1-year mortality. Design A population-based, historical cohort study of individuals who underwent surgical repair of a hip fracture that used the computerized medical record linkage system of the Rochester Epidemiology Project. Setting Academic and community hospitals, outpatient offices, and nursing homes in Olmsted County, Minnesota. Participants Over the 15-year study period (1988-2002), 1,116 elderly adults underwent surgical repair of a hip fracture. Measurements At the end of the first 7 days after hip fracture repair, participants were classified into one of three groups: clinically verified MI (cv-MI), subclinical myocardial ischemia, and no myocardial ischemia. One-year mortality was compared between these groups. Multivariate models assessed risk factors for early postoperative cv-MI and 1-year mortality. Results Within the first 7 days after hip fracture repair, 116 (10.4%) participants experienced cv-MI and 41 (3.7%) subclinical myocardial ischemia. Overall 1-year mortality was 22%, with no difference between those with subclinical myocardial ischemia and those with no myocardial ischemia. One-year mortality for those with cv-MI (35.8%) was significantly higher than for the other two groups. Occurrence of early postoperative cv-MI, male sex, and history of heart failure or dementia were independently associated with greater 1-year mortality, whereas prefracture home residence and preoperative higher hemoglobin were protective. Conclusion Rates of early postoperative, cv-MI after hip fracture repair exceed rates after other major orthopedic surgeries and are independently associated with greater 1-year mortality.

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