Myeloma-related Kidney Disease

Nelson Leung, Samih H. Nasr

Research output: Contribution to journalReview article

32 Scopus citations


Multiple myeloma is a malignant plasma cell disorder characterized by the overproduction of monoclonal proteins. The kidney is 1 of the major target organs of multiple myeloma. Most often, this is the result of the monoclonal proteins, which can injure the kidney via several mechanisms. In some cases, direct invasion by myeloma cells and/or bone marrow cells can also result in kidney injury. A kidney biopsy can help distinguish the various myeloma-related kidney diseases and aid in the treatment plan.

Original languageEnglish (US)
Pages (from-to)36-47
Number of pages12
JournalAdvances in Chronic Kidney Disease
Issue number1
StatePublished - Jan 1 2014


  • Amyloidosis
  • Cast nephropathy
  • Kidney
  • MIDD
  • Multiple myeloma

ASJC Scopus subject areas

  • Nephrology

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