My headache is gone, but my leg now hurts: Fatal Forty DDI: Methysergide, erythromycin, CYP3A4

Jessica D. Lorenz; Juraj Sprung; Wayne T. Nicholson

doi:10.1007/978-1-4614-7495-1_67

My headache is gone, but my leg now hurts: Fatal Forty DDI: Methysergide, erythromycin, CYP3A4

Jessica D. Lorenz, Juraj Sprung, Wayne T. Nicholson

Anesthesiology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This case discusses the pharmacokinetic interaction between methysergide and erythromycin resulting in vasospasm. Merthysergide is a cytochrome P450 3A4 substrate and erythromycin is a 3A4 inhibitor.

Original language	English (US)
Title of host publication	A Case Approach to Perioperative Drug-Drug Interactions
Publisher	Springer New York
Pages	321-325
Number of pages	5
ISBN (Electronic)	9781461474951
ISBN (Print)	9781461474944
DOIs	https://doi.org/10.1007/978-1-4614-7495-1_67
State	Published - Sep 15 2015

ASJC Scopus subject areas

General Medicine

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10.1007/978-1-4614-7495-1_67

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abstract = "This case discusses the pharmacokinetic interaction between methysergide and erythromycin resulting in vasospasm. Merthysergide is a cytochrome P450 3A4 substrate and erythromycin is a 3A4 inhibitor.",

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My headache is gone, but my leg now hurts: Fatal Forty DDI: Methysergide, erythromycin, CYP3A4

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