Mutation of the aromatic amino acid interacting with adenine moiety of ATP to a polar residue alters the properties of multidrug resistance protein 1

Medicine & Life Sciences

• Aromatic Amino Acids 100%
• Adenine 82%
• ATP Binding Cassette Transporter, Subfamily B, Member 1 77%
• Adenosine Triphosphate 54%
• Mutation 39%
• multidrug resistance-associated protein 1 21%
• Leukotriene C4 19%
• Cysteine 18%
• ATP-Binding Cassette Transporters 17%
• Histidine 11%
• Cystic Fibrosis Transmembrane Conductance Regulator 6%
• Chloride Channels 6%
• Serine 4%
• Nucleotides 4%
• Proteins 3%

Chemical Compounds

• Aromatic Amino Acid 81%
• Adenine 64%
• Mutation 59%
• Resistance 44%
• Leukotriene C4 40%
• Cysteine Residue 36%
• Protein 28%
• Substitution Reaction 27%
• Histidine 16%
• Amino-Acid Residue 15%
• Serine Residue 11%
• Solute 7%