Multivessel spontaneous coronary artery dissection associated with hormonal infertility therapy in a 39-year-old female

Evan L. Hardegree; Marysia S. Tweet; Sharonne N. Hayes; Rajiv Gulati; Garvan C. Kane

doi:10.1016/j.jccase.2012.01.003

Multivessel spontaneous coronary artery dissection associated with hormonal infertility therapy in a 39-year-old female

Evan L. Hardegree, Marysia S. Tweet, Sharonne N. Hayes, Rajiv Gulati, Garvan C. Kane

Cardiovascular Medicine

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Spontaneous coronary artery dissection (SCAD) is a rare and potentially lethal cause of chest pain and myocardial infarction in healthy young individuals. It more commonly affects females and has been correlated with hormonally-induced connective tissue changes in pregnancy and oral contraceptive use. We present the case of a previously healthy 39-year-old woman with multivessel SCAD associated with recent clomiphene and gonadotropin therapy for infertility, which is not a previously reported association, and we assert that this should be in the differential diagnosis of such patients with chest pain or myocardial infarction.

Original language	English (US)
Pages (from-to)	e69-e72
Journal	Journal of Cardiology Cases
Volume	5
Issue number	2
DOIs	https://doi.org/10.1016/j.jccase.2012.01.003
State	Published - Apr 2012

Keywords

Acute coronary syndrome
Myocardial infarction
Spontaneous coronary artery dissection
Women's health

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.jccase.2012.01.003

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title = "Multivessel spontaneous coronary artery dissection associated with hormonal infertility therapy in a 39-year-old female",

abstract = "Spontaneous coronary artery dissection (SCAD) is a rare and potentially lethal cause of chest pain and myocardial infarction in healthy young individuals. It more commonly affects females and has been correlated with hormonally-induced connective tissue changes in pregnancy and oral contraceptive use. We present the case of a previously healthy 39-year-old woman with multivessel SCAD associated with recent clomiphene and gonadotropin therapy for infertility, which is not a previously reported association, and we assert that this should be in the differential diagnosis of such patients with chest pain or myocardial infarction.",

keywords = "Acute coronary syndrome, Myocardial infarction, Spontaneous coronary artery dissection, Women's health",

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AU - Hardegree, Evan L.

AU - Tweet, Marysia S.

AU - Hayes, Sharonne N.

AU - Gulati, Rajiv

AU - Kane, Garvan C.

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N2 - Spontaneous coronary artery dissection (SCAD) is a rare and potentially lethal cause of chest pain and myocardial infarction in healthy young individuals. It more commonly affects females and has been correlated with hormonally-induced connective tissue changes in pregnancy and oral contraceptive use. We present the case of a previously healthy 39-year-old woman with multivessel SCAD associated with recent clomiphene and gonadotropin therapy for infertility, which is not a previously reported association, and we assert that this should be in the differential diagnosis of such patients with chest pain or myocardial infarction.

AB - Spontaneous coronary artery dissection (SCAD) is a rare and potentially lethal cause of chest pain and myocardial infarction in healthy young individuals. It more commonly affects females and has been correlated with hormonally-induced connective tissue changes in pregnancy and oral contraceptive use. We present the case of a previously healthy 39-year-old woman with multivessel SCAD associated with recent clomiphene and gonadotropin therapy for infertility, which is not a previously reported association, and we assert that this should be in the differential diagnosis of such patients with chest pain or myocardial infarction.

KW - Acute coronary syndrome

KW - Myocardial infarction

KW - Spontaneous coronary artery dissection

KW - Women's health

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Multivessel spontaneous coronary artery dissection associated with hormonal infertility therapy in a 39-year-old female

Abstract

Keywords

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