Multivessel spontaneous coronary artery dissection associated with hormonal infertility therapy in a 39-year-old female

Evan L. Hardegree, Marysia Tweet, Sharonne N. Hayes, Rajiv Gulati, Garvan M Kane

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Spontaneous coronary artery dissection (SCAD) is a rare and potentially lethal cause of chest pain and myocardial infarction in healthy young individuals. It more commonly affects females and has been correlated with hormonally-induced connective tissue changes in pregnancy and oral contraceptive use. We present the case of a previously healthy 39-year-old woman with multivessel SCAD associated with recent clomiphene and gonadotropin therapy for infertility, which is not a previously reported association, and we assert that this should be in the differential diagnosis of such patients with chest pain or myocardial infarction.

Original languageEnglish (US)
JournalJournal of Cardiology Cases
Volume5
Issue number2
DOIs
StatePublished - Apr 2012

Fingerprint

Chest Pain
Infertility
Myocardial Infarction
Clomiphene
Oral Contraceptives
Gonadotropins
Connective Tissue
Differential Diagnosis
Pregnancy
Therapeutics
Spontaneous Coronary Artery Dissection

Keywords

  • Acute coronary syndrome
  • Myocardial infarction
  • Spontaneous coronary artery dissection
  • Women's health

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

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abstract = "Spontaneous coronary artery dissection (SCAD) is a rare and potentially lethal cause of chest pain and myocardial infarction in healthy young individuals. It more commonly affects females and has been correlated with hormonally-induced connective tissue changes in pregnancy and oral contraceptive use. We present the case of a previously healthy 39-year-old woman with multivessel SCAD associated with recent clomiphene and gonadotropin therapy for infertility, which is not a previously reported association, and we assert that this should be in the differential diagnosis of such patients with chest pain or myocardial infarction.",
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AU - Hardegree, Evan L.

AU - Tweet, Marysia

AU - Hayes, Sharonne N.

AU - Gulati, Rajiv

AU - Kane, Garvan M

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AB - Spontaneous coronary artery dissection (SCAD) is a rare and potentially lethal cause of chest pain and myocardial infarction in healthy young individuals. It more commonly affects females and has been correlated with hormonally-induced connective tissue changes in pregnancy and oral contraceptive use. We present the case of a previously healthy 39-year-old woman with multivessel SCAD associated with recent clomiphene and gonadotropin therapy for infertility, which is not a previously reported association, and we assert that this should be in the differential diagnosis of such patients with chest pain or myocardial infarction.

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