Multisensory integration in migraine

Research output: Contribution to journalReview articlepeer-review

60 Scopus citations


Purpose of Review: Migraine attacks consist of head pain and hypersensitivities to somatosensory, visual, auditory, and olfactory stimuli. Investigating how the migraine brain simultaneously processes and responds to multiple incoming stimuli may yield insights into migraine pathophysiology and migraine symptoms. Recent Findings: The presence and intensity of hypersensitivity to one stimulus type are positively associated with the presence and intensity of hypersensitivities to other stimuli and to headache intensity. Furthermore, exposure to visual, auditory, and olfactory stimuli can trigger migraine attacks. These relationships suggest a role for multisensory integration in migraine. Summary: Multisensory integration of somatosensory, visual, auditory, and olfactory stimuli by the migraine brain may be an important concept for understanding migraine.

Original languageEnglish (US)
Pages (from-to)248-253
Number of pages6
JournalCurrent opinion in neurology
Issue number3
StatePublished - Jun 2013


  • cutaneous allodynia
  • migraine
  • migraine pathophysiology
  • multisensory integration
  • sensitization

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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