Abstract
Multiple myeloma (MM) is an uncommon malignant plasma cell disorder that often presents in older adults. An accurate diagnosis is critical as a spectrum of plasma cell disorders have been defined, including monoclonal gammopathy of undetermined significance, smouldering/asymptomatic multiple myeloma, multiple myeloma, and plasma cell leukemia. Although multiple myeloma is incurable disease, survival over 7 years is possible, during which patients can enjoy a good quality of life. Many therapeutic options now exist for individuals with MM who are ineligible for autologous stem cell transplantation; these include adding thalidomide, bortezomib, and lenalidomide to the current standard ofmelphalan and prednisone.
Original language | English (US) |
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Pages (from-to) | 382-388 |
Number of pages | 7 |
Journal | Geriatrics and Aging |
Volume | 12 |
Issue number | 8 |
State | Published - Sep 2009 |
Keywords
- MGUS
- Multiple myeloma
- Older adults
- Plasma cell leukemia
- Supportive care
ASJC Scopus subject areas
- Aging
- Gerontology
- Geriatrics and Gerontology